Mock B A, Givol D, D'Hoostelaere L A, Huppi K, Seldin M F, Gurfinkel N, Unger T, Potter M, Mushinski J F
Laboratory of Genetics, National Cancer Institute, Bethesda, MD 20892.
Cytogenet Cell Genet. 1988;47(1-2):11-5. doi: 10.1159/000132495.
Two bcl-2 alleles have been identified in inbred strains of mice by restriction fragment length polymorphism (RFLP). Analysis of a bcl-2 RFLP in a series of bilineal congenic strains (C.D2), developed as a tool for chromosomal mapping studies, revealed linkage of bcl-2 to the Idh-1/Pep-3 region of murine chromosome 1. The co-segregation of bcl-2 alleles with allelic forms of two other chromosome 1 loci, Ren-1,2 and Spna-1, in a set of back-cross progeny, positions bcl-2 7.8 cM centromeric from Ren-1,2.
