Kryshtafovych Andriy, Albrecht Reinhard, Baslé Arnaud, Bule Pedro, Caputo Alessandro T, Carvalho Ana Luisa, Chao Kinlin L, Diskin Ron, Fidelis Krzysztof, Fontes Carlos M G A, Fredslund Folmer, Gilbert Harry J, Goulding Celia W, Hartmann Marcus D, Hayes Christopher S, Herzberg Osnat, Hill Johan C, Joachimiak Andrzej, Kohring Gert-Wieland, Koning Roman I, Lo Leggio Leila, Mangiagalli Marco, Michalska Karolina, Moult John, Najmudin Shabir, Nardini Marco, Nardone Valentina, Ndeh Didier, Nguyen Thanh-Hong, Pintacuda Guido, Postel Sandra, van Raaij Mark J, Roversi Pietro, Shimon Amir, Singh Abhimanyu K, Sundberg Eric J, Tars Kaspars, Zitzmann Nicole, Schwede Torsten
Genome Center, University of California, Davis, 451 Health Sciences Drive, Davis, California, 95616.
Department of Protein Evolution, Max Planck Institute for Developmental Biology, Tübingen, 72076, Germany.
Proteins. 2018 Mar;86 Suppl 1(Suppl 1):27-50. doi: 10.1002/prot.25392. Epub 2017 Oct 16.
The functional and biological significance of the selected CASP12 targets are described by the authors of the structures. The crystallographers discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP12 experiment.
所选半胱天冬酶12(CASP12)靶点的功能和生物学意义由这些结构的作者进行了描述。晶体学家讨论了靶点蛋白最有趣的结构特征,并评估了这些特征在提交给CASP12实验的预测中是否得到了正确再现。