小鼠11号染色体上的Hox-2同源异型盒基因复合体与Re紧密连锁。
The Hox-2 homeo box gene complex on mouse chromosome 11 is closely linked to Re.
作者信息
Hart C P, Dalton D K, Nichols L, Hunihan L, Roderick T H, Langley S H, Taylor B A, Ruddle F H
机构信息
Department of Biology, Yale University, New Haven, Connecticut 06511.
出版信息
Genetics. 1988 Feb;118(2):319-27. doi: 10.1093/genetics/118.2.319.
Abstract
Restriction fragment length polymorphisms have been identified between inbred strains of mice for the homeo box gene complex Hox-2. These genetic markers were used to follow the segregation of different Hox-2 alleles among recombinant inbred strains of mice and among the progeny of a three point genetic cross. The results place the Hoax-2 locus approximately 1 cM from the rex (Re) locus on mouse chromosome 11.
摘要
已在小鼠近交系中鉴定出同源框基因复合体Hox-2的限制性片段长度多态性。这些遗传标记用于追踪不同Hox-2等位基因在重组近交系小鼠以及三点遗传杂交后代中的分离情况。结果表明，Hoax-2基因座位于小鼠11号染色体上距rex（Re）基因座约1厘摩处。
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