Rochefort Aude, Boukthir Sarrah, Moullec Séverine, Meygret Alexandra, Adnani Yahia, Lavenier Dominique, Faili Ahmad, Kayal Samer
CIC-1414 INSERM, Université Rennes 1, Faculté de Médecine, Team GeRMO, Rennes, France.
CHU Rennes Service de Bactériologie et Hygiène Hospitalière, Rennes, France.
Genome Announc. 2017 Sep 28;5(39):e00957-17. doi: 10.1128/genomeA.00957-17.
While the incidence and invasiveness of type 75 group A (GAS) infections increased in French Brittany during 2013, we sequenced and analyzed the genomes of three independent strains isolated in 2009, 2012, and 2014, respectively. In this short-term evolution, genomic analysis evidenced mainly the integration of new phages encoding virulence factors.
虽然2013年法国布列塔尼地区A群75型(GAS)感染的发病率和侵袭性有所增加,但我们分别对2009年、2012年和2014年分离出的三株独立菌株的基因组进行了测序和分析。在这一短期进化过程中,基因组分析主要证明了编码毒力因子的新噬菌体的整合。