Harrewijn Anita, Schmidt Louis A, Westenberg P Michiel, Tang Alva, van der Molen Melle J W
Developmental and Educational Psychology, Leiden University, Wassenaarseweg 52, 2333 AK Leiden, The Netherlands; Leiden Institute for Brain and Cognition, Leiden University, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
Department of Psychology, Neuroscience & Behaviour, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada.
Biol Psychol. 2017 Oct;129:324-348. doi: 10.1016/j.biopsycho.2017.09.013. Epub 2017 Sep 28.
Social anxiety disorder (SAD) is characterized by information processing biases, however, their underlying neural mechanisms remain poorly understood. The goal of this review was to give a comprehensive overview of the most frequently studied EEG spectral and event-related potential (ERP) measures in social anxiety during rest, anticipation, stimulus processing, and recovery. A Web of Science search yielded 35 studies reporting on electrocortical measures in individuals with social anxiety or related constructs. Social anxiety was related to increased delta-beta cross-frequency correlation during anticipation and recovery, and information processing biases during early processing of faces (P1) and errors (error-related negativity). These electrocortical measures are discussed in relation to the persistent cycle of information processing biases maintaining SAD. Future research should further investigate the mechanisms of this persistent cycle and study the utility of electrocortical measures in early detection, prevention, treatment and endophenotype research.
社交焦虑障碍（SAD）的特征在于信息处理偏差，然而，其潜在的神经机制仍知之甚少。本综述的目的是全面概述在休息、预期、刺激处理和恢复期间社交焦虑中最常研究的脑电图频谱和事件相关电位（ERP）测量方法。通过科学网搜索得到35项关于社交焦虑或相关结构个体的电皮层测量的研究报告。社交焦虑与预期和恢复期间δ波-β波交叉频率相关性增加以及面部早期处理（P1）和错误（错误相关负波）期间的信息处理偏差有关。这些电皮层测量方法与维持社交焦虑障碍的信息处理偏差的持续循环相关进行了讨论。未来的研究应进一步调查这种持续循环的机制，并研究电皮层测量方法在早期检测、预防、治疗和内表型研究中的效用。
