Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India.
Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli 620020, Tamil Nadu, India.
J Trace Elem Med Biol. 2017 Dec;44:125-131. doi: 10.1016/j.jtemb.2017.07.001. Epub 2017 Jul 8.
Adverse effects of nanoparticles on aquatic environment and organisms have drawn much special attention to many researches. Aluminium oxide nanoparticles (AlO-NPs) have potential uses in varied fields and are seen entering into the ecosystem. Their potential toxicity to the freshwater fish is not much studied. Hence this study was framed to investigate the effect AlO NPs on freshwater fish Oreochromis mossambicus in terms of sub lethal toxicity, histological changes and hepato somatic index (HSI) under laboratory conditions. Fishes were exposed to varying concentrations of AlO NPs for 96hr. LC value was found to be in between 235 and 245ppm. The findings of the present work showed that the NPs were accumulated in the fish liver and caused major histological anomalies such as structural alterations in the portal vein, necrotic hepatocytes, vacuolation, aggregation of blood cells and melanomacrophages. Significant histological alterations were observed in the highest concentration. Our results evidenced that the AlO NPs in the aquatic environment affects the health condition of the fishes.
纳米粒子对水生环境和生物的不良影响引起了许多研究的特别关注。氧化铝纳米粒子（AlO-NPs）在多个领域具有潜在的用途，并被认为进入了生态系统。它们对淡水鱼的潜在毒性尚未得到充分研究。因此，本研究旨在探讨氧化铝纳米粒子（AlO-NPs）对淡水鱼奥利亚罗非鱼（Oreochromis mossambicus）在亚致死毒性、组织学变化和肝体比（HSI）方面的影响，在实验室条件下进行。鱼类暴露于不同浓度的 AlO-NPs 中 96 小时。LC 值介于 235 和 245ppm 之间。目前工作的结果表明，纳米粒子在鱼肝脏中积累，并导致主要的组织异常，如门脉结构改变、坏死肝细胞、空泡化、血细胞和黑色素巨噬细胞聚集。在最高浓度下观察到明显的组织学改变。我们的结果表明，水生环境中的 AlO-NPs 会影响鱼类的健康状况。
