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二氧化硅纳米颗粒对奥利亚罗非鱼的肝毒性反应。

Hepatic toxicological responses of SiO nanoparticle on Oreochromis mossambicus.

机构信息

Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Affiliated to Bharathidasan University, Tiruchirappalli, 620020, Tamil Nadu, India.

Environmental Research Laboratory, P.G. and Research Department of Zoology, Jamal Mohamed College (Autonomous), Affiliated to Bharathidasan University, Tiruchirappalli, 620020, Tamil Nadu, India; Department of Zoology, Bharat Ratna Puratchi Thalaivar Dr. MGR Govt. Arts and Science College, Palacode, Dharmapuri, 636808, Tamil Nadu, India.

出版信息

Environ Toxicol Pharmacol. 2020 Aug;78:103398. doi: 10.1016/j.etap.2020.103398. Epub 2020 Apr 21.

DOI:10.1016/j.etap.2020.103398
PMID:32361396
Abstract

The present study was carried out to investigate the impact of various concentrations of SiO nanoparticles (SiO NP) on the commonly available freshwater fish Oreochromis mossambicus. The 96 h median lethal concentration (LC) of SiO NP was found to be between 270-280 ppm. This novel study has demonstrated histological alterations in the hepatic tissues and a dose-dependent depletion of tissue protein content and an elevated transaminases activity in the treated fish, which has facilitated understanding of the impact of SiO NP in O. mossambicus.

摘要

本研究旨在探讨不同浓度的 SiO 纳米颗粒 (SiO NP) 对常见淡水鱼类奥利亚罗非鱼的影响。结果表明,SiO NP 的 96 h 半致死浓度 (LC) 在 270-280ppm 之间。这项新研究表明,SiO NP 处理的鱼肝脏组织出现组织学改变,组织蛋白含量呈剂量依赖性减少,转氨酶活性升高,这有助于了解 SiO NP 对奥利亚罗非鱼的影响。

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