Singh Yogen
Department of Neonatology and Pediatric Cardiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
University of Cambridge Clinical School of Medicine, Cambridge, United Kingdom.
Front Pediatr. 2017 Sep 15;5:201. doi: 10.3389/fped.2017.00201. eCollection 2017.
Hemodynamic instability and inadequate cardiac performance are common in critically ill children. The clinical assessment of hemodynamic status is reliant upon physical examination supported by the clinical signs such as heart rate, blood pressure, capillary refill time, and measurement of the urine output and serum lactate. Unfortunately, all of these parameters are surrogate markers of cardiovascular well-being and they provide limited direct information regarding the adequacy of blood flow and tissue perfusion. A bedside point-of-care echocardiography can provide real-time hemodynamic information by assessing cardiac function, loading conditions (preload and afterload) and cardiac output. The echocardiography has the ability to provide longitudinal functional assessment in real time, which makes it an ideal tool for monitoring hemodynamic assessment in neonates and children. It is indispensable in the management of patients with shock, pulmonary hypertension, and patent ductus arteriosus. The echocardiography is the gold standard diagnostic tool to assess hemodynamic stability in patients with pericardial effusion, cardiac tamponade, and cardiac abnormalities such as congenital heart defects or valvar disorders. The information from echocardiography can be used to provide targeted treatment in intensive care settings such as need of fluid resuscitation versus inotropic support, choosing appropriate inotrope or vasopressor, and in providing specific interventions such as selective pulmonary vasodilators in pulmonary hypertension. The physiological information gathered from echocardiography may help in making timely, accurate, and appropriate diagnosis and providing specific treatment in sick patients. There is no surprise that use of bedside point-of-care echocardiography is rapidly gaining interest among neonatologists and intensivists, and it is now being used in clinical decision making for patients with hemodynamic instability. Like any other investigation, it has certain limitations and the most important limitation is its intermittent nature. Sometimes acquiring high quality images for precise functional assessment in a ventilated child can be challenging. Therefore, it should be used in conjunction with the existing tools (physical examination and clinical parameters) for hemodynamic assessment while making clinical decisions.
血流动力学不稳定和心脏功能不全在危重症儿童中很常见。血流动力学状态的临床评估依赖于体格检查,并辅以心率、血压、毛细血管再充盈时间等临床体征,以及尿量和血清乳酸的测量。不幸的是,所有这些参数都是心血管健康的替代指标,它们提供的关于血流充足性和组织灌注的直接信息有限。床旁即时超声心动图可以通过评估心脏功能、负荷状态(前负荷和后负荷)和心输出量来提供实时血流动力学信息。超声心动图能够实时提供纵向功能评估,这使其成为监测新生儿和儿童血流动力学评估的理想工具。它在休克、肺动脉高压和动脉导管未闭患者的管理中不可或缺。超声心动图是评估心包积液、心脏压塞以及先天性心脏病或瓣膜疾病等心脏异常患者血流动力学稳定性的金标准诊断工具。超声心动图提供的信息可用于在重症监护环境中进行针对性治疗,如确定是否需要液体复苏还是使用血管活性药物支持、选择合适的血管活性药物或血管加压药,以及在肺动脉高压中提供特定干预措施,如选择性肺血管扩张剂。从超声心动图收集的生理信息可能有助于对患病患者做出及时、准确和适当的诊断并提供特定治疗。毫不奇怪,床旁即时超声心动图的使用在新生儿科医生和重症监护医生中迅速受到关注,现在它正被用于血流动力学不稳定患者的临床决策。与任何其他检查一样,它有一定的局限性,最重要的局限性是其间歇性。有时,在通气的儿童中获取高质量图像以进行精确的功能评估可能具有挑战性。因此,在做出临床决策时,应将其与现有的血流动力学评估工具(体格检查和临床参数)结合使用。