Chen Yumei, Chen Ruohua, Zhou Xiang, Liu Jianjun, Huang Gang
Department of Nuclear Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Department of Cancer Metabolism, Institute of Health Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School Medicine, Shanghai, China.
Oncotarget. 2017 Mar 16;8(38):64417-64426. doi: 10.18632/oncotarget.16295. eCollection 2017 Sep 8.
To examine the development and application of systems combining positron emission and x-ray-computed tomography systems (PET/CTs) in mainland China.
Using a questionnaire, we surveyed Chinese medical institutions on a variety topics relating to their PET/CT systems and its use. The respondents had PET/CTs installed and in clinical use before 31 December 2015. We examined the clinical scenarios to which Chinese PET/CTs were applied by reviewing the related Chinese and international literature from the start of 1995 to the end of 2013; these papers were found by searching the Wanfang and PubMed databases, respectively. The data were then classified and analyzed statistically.
At the end of 2015, there were 240 PET/CTs and 101 medical cyclotrons in mainland China. The total number of PET studies performed in 2015 was 469,364. The main clinical applications of PET were found to be diagnostic fludeoxyglucose (F-FDG) imaging and oncological imaging. A minority of PET/CT studies were performed using C-choline and other imaging agents. The number of papers relating to clinical use of PET/CT in mainland China increased each year over the period of study, in both the Chinese and international literature. Despite this progress, important problems were also apparent, including unbalanced regional development and the limited quality of the research.
This study provides detailed information for understanding the development PET/CT technology in mainland China, along with its geographical distribution and clinical application. It may thus prove a useful reference for all those involved in planning the future of PET/CT in China.
探讨正电子发射断层显像与X射线计算机断层扫描系统(PET/CT)联用系统在中国大陆的发展与应用情况。
我们通过问卷调查的方式,就与PET/CT系统及其使用相关的多个主题对中国医疗机构进行了调查。调查对象的PET/CT在2015年12月31日前已安装并投入临床使用。我们通过分别检索万方数据库和PubMed数据库,回顾1995年初至2013年末的相关中国及国际文献,研究中国大陆PET/CT的临床应用场景;随后对数据进行分类并进行统计分析。
截至2015年底,中国大陆共有240台PET/CT和101台医用回旋加速器。2015年PET检查的总数为469,364例。PET的主要临床应用为诊断性氟脱氧葡萄糖(F-FDG)显像和肿瘤显像。少数PET/CT检查使用了碳-胆碱及其他显像剂。在研究期间,中国大陆有关PET/CT临床应用的论文数量在中文和国际文献中均逐年增加。尽管取得了这一进展,但一些重要问题也很明显,包括区域发展不平衡以及研究质量有限。
本研究为了解中国大陆PET/CT技术的发展、地理分布及临床应用提供了详细信息。因此,它可能对所有参与规划中国PET/CT未来发展的人员具有有用的参考价值。