Fan Tao, Song Ying Jie, Liu Xiu Li, Zhou Jun, Yang Hong, Wei Ya Nan, Wang Chao Qi
Department of Oncology, First People's Hospital of Yichang, Yichang 443000, Hubei Province, China.
Department of General Surgery, First People's Hospital of Yichang, Yichang 443000, Hubei Province, China.
J Coll Physicians Surg Pak. 2017 Sep;27(9):S122-S124.
Merkel cell carcinoma (MCC) is a rare aggressive cutaneous neuroendocrine carcinoma that typically arises in sunexposed areas of the skin. Herein, we present three cases of primary MCC of the cheek. Case 1 had multiple nodules and mild swelling on the left cheek and eyelids, the patient did not receive any treatment and died after 10 months. Case 2 presented with nodule on patient's left cheek, which increased gradually. The patient was treated with surgical resection from the tumor edge 0.3 cm and skin flap transplantation, she died after 21 months. Case 3 presented with a nodule without any symptoms on patient's left cheek, she was treated with surgical resection and the left cheek was reconstructed with a free flap of tissue. Outpatient follow-up did not show any recurrence and metastasis. The authors report the clinical, histopathological, therapy, prognosis features of MCC, and reviewed with literature.
默克尔细胞癌（MCC）是一种罕见的侵袭性皮肤神经内分泌癌，通常发生于皮肤暴露于阳光的部位。在此，我们报告3例颊部原发性MCC病例。病例1左侧脸颊和眼睑有多个结节及轻度肿胀，患者未接受任何治疗，10个月后死亡。病例2患者左侧脸颊出现结节，且逐渐增大。患者接受了距肿瘤边缘0.3 cm的手术切除及皮瓣移植治疗，21个月后死亡。病例3患者左侧脸颊出现一个无症状结节，接受了手术切除，并用游离组织瓣重建左侧脸颊。门诊随访未发现任何复发和转移情况。作者报告了MCC的临床、组织病理学、治疗及预后特征，并进行了文献复习。
