Park Tae Jun, Ki Sae Hwi, Yoon Jin Myung
Department of Plastic and Reconstructive Surgery, Inha University Hospital.
Department of Plastic and Reconstructive Surgery, Inha University School of Medicine, Incheon, Korea.
J Craniofac Surg. 2023;34(5):e497-e499. doi: 10.1097/SCS.0000000000009367. Epub 2023 May 22.
Merkel cell carcinoma (MCC) is a rare and very aggressive skin cancer. An 83-year-old female presented with a 1.5 cm-sized non-tender mass on her left cheek and was diagnosed with MCC. The margin of MCC was well-defined and there was no cervical node metastasis on pre-operative computed tomography. Three weeks after the first visit, the mass rapidly increased in size. We checked the magnetic resonance imaging, a rapid-growing 2.5 cm sized nodular region and metastatic cervical lymph node were found. We performed wide excision of the MCC and neck lymph need dissection with multidisciplinary cooperation. The soft tissue defect was about 6.0×5.0 cm 2 in size and reconstructed with radial forearm free flap. On permanent biopsy, the size of MCC was 3.0×2.3 cm 2 . There was no recurrence of MCC with radiation therapy during an 18-month follow-up. We experienced an older patient with a rapid - growing MCC and cervical lymph node metastasis in a brief time. With our experience, we discuss the evaluation and treatment plan of the rapid-growing MCC for good results.
默克尔细胞癌（MCC）是一种罕见且侵袭性很强的皮肤癌。一名83岁女性患者左脸颊出现一个1.5厘米大小的无痛性肿块，被诊断为MCC。MCC边界清晰，术前计算机断层扫描未发现颈部淋巴结转移。初诊三周后，肿块迅速增大。我们检查了磁共振成像，发现一个快速生长的2.5厘米大小的结节区域和转移性颈部淋巴结。我们在多学科合作下对MCC进行了广泛切除并清扫了颈部淋巴结。软组织缺损面积约为6.0×5.0平方厘米，采用游离桡侧前臂皮瓣进行修复。在永久活检中，MCC大小为3.0×2.3平方厘米。在18个月的随访期间，接受放射治疗的MCC未复发。我们遇到了一位老年患者，其MCC在短时间内快速生长并出现颈部淋巴结转移。基于我们的经验，我们讨论了快速生长型MCC的评估和治疗方案以取得良好效果。
