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尼日利亚东南部纽维市纳姆迪·阿齐克韦大学教学医院患者对脐带血捐献及输血应用的认知与态度

Knowledge and attitude of donating and using cord blood for transfusion among patients attending Nnamdi Azikiwe University Teaching Hospital, Nnewi, South East Nigeria.

作者信息

Okocha Chide E, Ezeama Nkiru N, Aneke John C, Onubogu Chinyere U, Okafor Charles I, Egbunike Chijioke G

机构信息

Department of Haematology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.

Department of Community Health, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.

出版信息

Asian J Transfus Sci. 2017 Jul-Dec;11(2):162-170. doi: 10.4103/ajts.AJTS_113_16.

Abstract

BACKGROUND

Allogeneic blood for transfusion is in short supply in most parts of the developing world. Cord blood for transfusion can be a significant source of blood supply to our health institutions.

AIMS

This study aims to investigate the knowledge and attitude to the donation and use of umbilical cord blood (UCB) for transfusion among the patients receiving services in a tertiary health institution in South-East Nigeria.

MATERIALS AND METHODS

This was a cross-sectional study; an anonymous structured questionnaire was used. A total of 549 consenting patients randomly selected from the antenatal, postnatal, sickle cell clinics, and wards were the subjects. Statistical analysis of the data was done using SPSS version 20.0.

RESULTS

The mean age of the participants was 31.9 ± 9.5 years. The majority were females (77.2%), married (86.4%). About 26.2% of the respondents were willing to accept UCB for transfusion to them or their child. Following counseling, the acceptance rate increased to 71.5%. Most of the respondents (80.0%) were willing to donate the UCB of their baby; or be tested for HIV (93.3%), if necessary. Educational level was significantly associated with knowledge of UCB. After logistic regression, occupation, and gender were significantly associated with acceptance of UCB for transfusion. Up to 52% belonged to low income family background, approximately 150 US dollars monthly family income (50,000 naira).

CONCLUSION

The knowledge and acceptance of UCB for transfusion are low in our environment. However, proper counseling and public enlightenment could change this attitude.

摘要

背景

在发展中世界的大部分地区,用于输血的异体血供应短缺。用于输血的脐带血可以成为我们医疗机构血液供应的重要来源。

目的

本研究旨在调查尼日利亚东南部一家三级医疗机构中接受服务的患者对脐带血捐赠和用于输血的知识及态度。

材料与方法

这是一项横断面研究;使用了一份匿名结构化问卷。从产前、产后、镰状细胞病诊所和病房中随机选取的549名同意参与的患者作为研究对象。使用SPSS 20.0版本对数据进行统计分析。

结果

参与者的平均年龄为31.9±9.5岁。大多数为女性(77.2%),已婚(86.4%)。约26.2%的受访者愿意接受脐带血输给他们自己或他们的孩子。经过咨询后,接受率提高到71.5%。大多数受访者(80.0%)愿意捐赠其婴儿的脐带血;或者在必要时接受艾滋病毒检测(93.3%)。教育水平与脐带血知识显著相关。经过逻辑回归分析,职业和性别与接受脐带血输血显著相关。高达52%的人属于低收入家庭背景,家庭月收入约150美元(50,000奈拉)。

结论

在我们的环境中,对脐带血用于输血的知识和接受度较低。然而,适当的咨询和公众宣传可以改变这种态度。

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Umbilical cord blood transplantation: the first 25 years and beyond.脐带血移植:25 年及以后的发展历程。
Blood. 2013 Jul 25;122(4):491-8. doi: 10.1182/blood-2013-02-453175. Epub 2013 May 14.
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Umbilical cord blood transplantation for children with thalassemia and sickle cell disease.脐带血移植治疗地中海贫血和镰状细胞病患儿。
Biol Blood Marrow Transplant. 2011 Sep;17(9):1375-82. doi: 10.1016/j.bbmt.2011.01.012. Epub 2011 Jan 28.

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