Hassall O, Ngina L, Kongo W, Othigo J, Mandaliya K, Maitland K, Bates I
Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya.
Vox Sang. 2008 Feb;94(2):125-31. doi: 10.1111/j.1423-0410.2007.01012.x. Epub 2007 Dec 14.
Severe anaemia, for which a blood transfusion can be life saving, is common in hospitalized children in sub-Saharan Africa but blood for transfusion is often in short supply. Umbilical cord blood is usually thrown away but could be a useful source of red cells for small volume transfusions in young children in this setting. The objective of this study was to evaluate the attitudes of women using the maternity services of the provincial hospital in Mombasa, Kenya, towards cord blood donation and transfusion, and essential aspects of this process including informed consent and the acceptability of screening for human immunodeficiency virus (HIV) infection.
A structured questionnaire was developed based on data provided by focus group discussions with women attending the hospital's maternity unit and administered to women who had recently delivered at the hospital.
Of the 180 women who completed a questionnaire, the donation and transfusion of cord blood were acceptable to 81% and 78%, respectively. Ninety per cent of women who supported cord blood donation were willing to undergo further HIV testing at the time of delivery. Seventy-seven per cent of women wanted informed consent to be sought for cord blood donation and 66% of these felt they could make this decision alone.
The donation of umbilical cord blood and its transfusion are acceptable to the majority of women delivering at Coast Provincial General Hospital, Mombasa. Findings from the study will benefit the planned cord blood donation programme at this facility.
严重贫血在撒哈拉以南非洲地区住院儿童中很常见，输血可能挽救生命，但用于输血的血液往往供应短缺。脐带血通常被丢弃，但在这种情况下，它可能是为幼儿进行小容量输血的有用红细胞来源。本研究的目的是评估肯尼亚蒙巴萨省医院使用产科服务的妇女对脐带血捐献和输血的态度，以及这一过程的重要方面，包括知情同意和人类免疫缺陷病毒（HIV）感染筛查的可接受性。
根据与该医院产科病房的妇女进行焦点小组讨论提供的数据，制定了一份结构化问卷，并对最近在该医院分娩的妇女进行了问卷调查。
在完成问卷的180名妇女中，分别有81%和78%的人接受脐带血捐献和输血。支持脐带血捐献的妇女中有90%愿意在分娩时接受进一步的HIV检测。77%的妇女希望在脐带血捐献时获得知情同意，其中66%的人认为她们可以独自做出这个决定。
蒙巴萨海岸省总医院大多数分娩妇女接受脐带血捐献及其输血。该研究结果将有助于该机构计划中的脐带血捐献项目。
