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阿普唑仑辅助治疗伴有惊恐焦虑的精神分裂症：临床观察及发病机制探讨

Adjunctive alprazolam for schizophrenia with panic anxiety: clinical observation and pathogenetic implications.

作者信息

Kahn J P, Puertollano M A, Schane M D, Klein D F

机构信息

Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032.

出版信息

Am J Psychiatry. 1988 Jun;145(6):742-4. doi: 10.1176/ajp.145.6.742.

DOI:10.1176/ajp.145.6.742
PMID:2897166
Abstract

Seven patients with schizophrenia and panic attacks all showed marked improvement of positive and negative schizophrenic symptoms when alprazolam was openly added to antipsychotic medication. Panic attacks may identify alprazolam-responsive schizophrenic patients and may define a distinct pathophysiologic subgroup.

摘要

7例患有精神分裂症和惊恐发作的患者在抗精神病药物治疗中加用阿普唑仑后，精神分裂症的阳性和阴性症状均有明显改善。惊恐发作可能提示对阿普唑仑有反应的精神分裂症患者，并可能界定一个独特的病理生理亚组。

相似文献

1
Adjunctive alprazolam for schizophrenia with panic anxiety: clinical observation and pathogenetic implications.阿普唑仑辅助治疗伴有惊恐焦虑的精神分裂症：临床观察及发病机制探讨
Am J Psychiatry. 1988 Jun;145(6):742-4. doi: 10.1176/ajp.145.6.742.
2
Schizophrenia, panic anxiety, and alprazolam.精神分裂症、惊恐焦虑症与阿普唑仑。
Am J Psychiatry. 1987 Apr;144(4):527-8. doi: 10.1176/ajp.144.4.527b.
3
Schizophrenia, panic attacks, and antidepressants.精神分裂症、惊恐发作与抗抑郁药。
Am J Psychiatry. 1989 Feb;146(2):279. doi: 10.1176/ajp.146.2.279a.
4
"Panic disorder" in schizophrenia.精神分裂症中的“惊恐障碍”
J Nerv Ment Dis. 1987 Oct;175(10):627-8.
5
Alprazolam in the treatment of panic attack patients with and without major depression.阿普唑仑治疗伴或不伴重度抑郁的惊恐障碍患者。
J Clin Psychiatry. 1988 Feb;49(2):66-8.
6
Emergence of depressive symptoms in patients receiving alprazolam for panic disorder.接受阿普唑仑治疗惊恐障碍的患者出现抑郁症状。
Am J Psychiatry. 1987 May;144(5):664-5. doi: 10.1176/ajp.144.5.664.
7
Treatment of panic attacks with alprazolam and propranolol.
Am J Psychiatry. 1984 Jul;141(7):900-1. doi: 10.1176/ajp.141.7.900.
8
Combination alprazolam-neuroleptic treatment of the positive and negative symptoms of schizophrenia.阿普唑仑与抗精神病药物联合治疗精神分裂症的阳性和阴性症状。
Am J Psychiatry. 1986 Jan;143(1):85-7. doi: 10.1176/ajp.143.1.85.
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Combined alprazolam and neuroleptic drug in treating schizophrenia.
Am J Psychiatry. 1986 Oct;143(10):1311-3. doi: 10.1176/ajp.143.10.aj143101311.
10
Alprazolam-neuroleptic combination in schizophrenia.阿普唑仑与抗精神病药物联合用于治疗精神分裂症
Am J Psychiatry. 1986 Nov;143(11):1501-2. doi: 10.1176/ajp.143.11.aj143111501.

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Correlates and management of comorbid anxiety disorders in schizophrenia.精神分裂症中共病焦虑障碍的相关因素及管理
Ind Psychiatry J. 2018 Jul-Dec;27(2):271-278. doi: 10.4103/ipj.ipj_66_17.
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Schizophrenia comorbid with panic disorder: evidence for distinct cognitive profiles.精神分裂症合并惊恐障碍：不同认知特征的证据。
Psychiatry Res. 2012 May 30;197(3):206-11. doi: 10.1016/j.psychres.2012.01.017. Epub 2012 Mar 13.
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Survey of the adjuvant use of benzodiazepines for treating outpatients with schizophrenia.苯二氮䓬类药物辅助治疗精神分裂症门诊患者的调查。
J Psychiatry Neurosci. 1993 Mar;18(2):82-4.
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Schizophrenia and the life cycle.
Community Ment Health J. 1995 Jun;31(3):249-62. doi: 10.1007/BF02188751.
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A review of evidence for GABergic predominance/glutamatergic deficit as a common etiological factor in both schizophrenia and affective psychoses: more support for a continuum hypothesis of "functional" psychosis.关于γ-氨基丁酸能占优势/谷氨酸能缺陷作为精神分裂症和情感性精神病共同病因因素的证据综述：对“功能性”精神病连续体假说的更多支持
Neurochem Res. 1991 Oct;16(10):1099-111. doi: 10.1007/BF00966587.
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The use of carbamazepine in the treatment of schizophrenic and schizoaffective psychoses: a review.卡马西平在精神分裂症和分裂情感性精神病治疗中的应用：综述
J Psychiatry Neurosci. 1992 Mar;17(1):1-14.