1 Hospital Universitario Infanta Leonor, Madrid, Spain.
2 Complutense University of Madrid, Spain.
J Atten Disord. 2019 Jul;23(9):1007-1016. doi: 10.1177/1087054717733046. Epub 2017 Oct 3.
In this multicenter, cross-sectional study, we aimed to investigate the quality of life (QoL) and the neuropsychological and clinical characteristics of adults with ADHD with different developmental pathways.
Our study sample included 25 control (healthy) participants, 31 patients with newly diagnosed ADHD without comorbidities (ADHD-C-D), 31 with newly diagnosed ADHD with comorbidities (ADHD+C-D), and 29 with previously diagnosed ADHD with comorbidities (ADHD+C+D).
Compared with controls, ADHDs had little differences in the attentional performance but showed higher impulsivity, more severe symptoms of depression and anxiety, and lower QoL. The ADHD+C-D group showed more severe symptoms of depression and anxiety than the ADHD+C+D group ( p = .037 and p = .008, respectively), and poorer QoL in the psychological health sphere ( p = .003).
Differences between ADHD and control subjects were particularly remarkable in mood symptoms and QoL. Previous diagnosis might have a positive impact on mood symptoms and QoL in ADHD adults.
在这项多中心、横断面研究中,我们旨在研究具有不同发展途径的成年 ADHD 患者的生活质量(QoL)以及神经心理学和临床特征。
我们的研究样本包括 25 名对照(健康)参与者、31 名无合并症的新诊断 ADHD 患者(ADHD-C-D)、31 名有合并症的新诊断 ADHD 患者(ADHD+C-D)和 29 名有先前诊断的合并症的 ADHD 患者(ADHD+C+D)。
与对照组相比,ADHD 患者的注意力表现差异不大,但表现出更高的冲动性、更严重的抑郁和焦虑症状以及更低的生活质量。ADHD+C-D 组比 ADHD+C+D 组有更严重的抑郁和焦虑症状(p=.037 和 p=.008),以及心理健康领域较差的生活质量(p=.003)。
ADHD 与对照组之间的差异在情绪症状和生活质量方面尤为明显。先前的诊断可能对 ADHD 成年患者的情绪症状和生活质量产生积极影响。