Healthcare Associated Infections and Antimicrobial Resistance, Public Health England, London, UK.
Healthcare Associated Infections and Antimicrobial Resistance, Public Health England, London, UK.
J Hosp Infect. 2018 Mar;98(3):228-231. doi: 10.1016/j.jhin.2017.09.021. Epub 2017 Sep 30.
Escherichia coli bacteraemia rates have been increasing in England. Using the national mandatory surveillance data for E. coli bacteraemia from 2012/13 to 2016/17, we aimed to estimate the incidence of E. coli bacteraemia and 30-day all-cause case fatality rate (CFR) by 2020/21 in the absence of new interventions to reduce infection rates. After controlling for age, sex, and hospital versus community-onset of infection, it is estimated that the incidence of E. coli bacteraemia will be 90.5 (95% PI: 89.8-91.3) per 100,000 population (N = 50,663), with an associated CFR of 11.5 (95% PI: 11.2-11.8) per 100,000 population (N = 6554), by 2020/21.
英格兰的大肠杆菌菌血症发病率一直在上升。利用 2012/13 至 2016/17 年全国强制性大肠杆菌菌血症监测数据，我们旨在估算在没有新干预措施降低感染率的情况下，到 2020/21 年大肠杆菌菌血症的发病率和 30 天全因病死率（CFR）。在控制年龄、性别和医院与社区感染的发病情况后，预计到 2020/21 年，每 10 万人中将有 90.5 例（95%置信区间：89.8-91.3）大肠杆菌菌血症（N=50663），相应的病死率为每 10 万人中有 11.5 例（95%置信区间：11.2-11.8）（N=6554）。
