Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
Cancer Discov. 2017 Oct;7(10):1067-1068. doi: 10.1158/2159-8290.CD-17-0887.
Pathways that stimulate metastasis of pancreatic cancer cells are critical for understanding tumor evolution and can serve as potential therapeutic targets. The microenvironment produces a host of metabolic perturbations and tropic factors that may play a formative role in this process. .
刺激胰腺癌细胞转移的途径对于理解肿瘤的进化至关重要,并且可以作为潜在的治疗靶点。微环境产生了大量的代谢干扰和营养因子,它们可能在这个过程中起着重要的作用。