Mahmoodnia Leila, Tamadon Mohammad Reza
Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Department of Internal Medicine, Semnan University of Medical Science, Semnan, Iran.
J Nephropathol. 2017 Jul;6(3):105-109. doi: 10.15171/jnp.2017.18. Epub 2017 Jan 5.
Numerous studies have reported the impact of obesity in the incidence of chronic kidney disease (CKD). Some studies have suggested the direct role of obesity in the incidence of CKD, while some other studies suggest an indirect effect caused by the effects of obesity on blood pressure and diabetes.
PubMed, EBSCO, Web of Science, directory of open access journals (DOAJ), EMBASE, and Google Scholar have been searched.
Recent studies have presented more strong evidences on the role of obesity on the incidence of CKD. The double role of obesity in the incidence of CKD has also been mentioned in some studies.
Such an additional effect arises from the impact of obesity on the incidence of some conditions and diseases such as cardiovascular disease, hypertension, and diabetes, which in turn are involved in the incidence of CKD and are considered as its risk factors.
众多研究报告了肥胖对慢性肾脏病（CKD）发病率的影响。一些研究表明肥胖在CKD发病中起直接作用，而其他一些研究则表明肥胖通过对血压和糖尿病的影响产生间接作用。
检索了PubMed、EBSCO、科学引文索引（Web of Science）、开放获取期刊目录（DOAJ）、荷兰医学文摘数据库（EMBASE）和谷歌学术。
近期研究提供了更多关于肥胖在CKD发病中作用的有力证据。一些研究也提到了肥胖在CKD发病中的双重作用。
这种额外作用源于肥胖对某些疾病如心血管疾病、高血压和糖尿病发病率的影响，而这些疾病又与CKD的发病有关并被视为其危险因素。
