Department of Medicine, University of Wisconsin, Madison, WI, USA.
Departments of Pediatrics and Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA.
Am J Transplant. 2018 Feb;18(2):486-491. doi: 10.1111/ajt.14524. Epub 2017 Nov 11.
About 99 000 people are waiting for a kidney in the United States, and many will die waiting. The concept of "imminent death" donation, a type of living donation, has been gaining attention among physicians, patients, and ethicists. We estimated the number of potential imminent death kidney donors at the University of Wisconsin Hospital and Clinics by assessing the number of annual deaths in individuals with normal kidney function. Based on a previous survey suggesting that one-third of patients might be willing to donate at imminent death, we estimate that between 76 and 396 people in the state of Wisconsin would be medically eligible and willing to donate each year at the time of imminent death. We extrapolated these numbers to all transplant centers in the United States, estimating that between 5925 and 31 097 people might be eligible and willing to donate each year. Our results suggest that allowing donation at imminent death and including discussions about organ donation in end-of-life planning could substantially reduce the nation's kidney waiting list while providing many more donors the opportunity to give this gift.
在美国,大约有 99000 人在等待肾脏,其中许多人将在等待中死亡。“即将死亡”捐赠的概念,即一种活体捐赠,已经引起了医生、患者和伦理学家的关注。我们通过评估肾功能正常的个体的年死亡人数,估计了威斯康星大学医院和诊所的潜在“即将死亡”的肾脏捐赠者数量。根据一项此前的调查显示,可能有三分之一的患者愿意在即将死亡时捐献器官,我们估计每年在即将死亡时,威斯康星州有 76 到 396 人在医学上有资格并愿意捐献。我们将这些数字推断到全美所有的移植中心,估计每年可能有 5925 到 31097 人有资格并愿意捐献。我们的研究结果表明,允许在即将死亡时进行捐赠,并将器官捐赠纳入临终规划,可以显著减少国家的肾脏等待名单,同时为更多的捐赠者提供机会,给予这个礼物。