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急性 I 型主动脉夹层修复术后远端吻合口新发入口的预后影响。

The prognostic impact of distal anastomotic new entry after acute type I aortic dissection repair.

机构信息

Department of Cardiovascular Surgery, The Sakakibara Heart Institute of Okayama, Okayama, Japan.

出版信息

Eur J Cardiothorac Surg. 2017 Nov 1;52(5):867-873. doi: 10.1093/ejcts/ezx223.

Abstract

OBJECTIVES

Distal anastomotic new entry (DANE) is considered to be one of the causes of patent false lumen (PFL) after acute type I aortic dissection repair. However, there have been few articles with regard to this important issue. We assessed the influence of PFL caused by DANE on long-term outcomes.

METHODS

One hundred twenty-two patients underwent emergency surgery for acute type I aortic dissection (2007-12). The in-hospital mortality was 8% (10 patients). Among the survivors, 93 patients (mean age 67 years) underwent enhanced computed tomography within 2 weeks after the operation. These patients were divided into 3 groups according to the status of the residual FL: those with a PFL with DANE (n = 19) or without DANE (n = 27) and those with a thrombosed FL (n = 47). Changes in descending aortic diameter were analysed between early and last follow-up images.

RESULTS

Aortic growth rate in the PFL with DANE group was greater than that of the other 2 groups (P < 0.05). The PFL with DANE group demonstrated a lower rate of freedom from dissection-related event of distal aorta (66% at 5 years) and enlargement of distal aortic lesions (62% at 5 years). There were no significant differences in late survival among the groups. PFL with DANE was one of the significant risk factors for distal aortic events.

CONCLUSIONS

PFL caused by DANE after acute type I aortic dissection repair showed greater aortic growth rate of the descending aorta and was one of the significant risk factors for distal aortic events.

摘要

目的

远端吻合口新入口(DANE)被认为是急性 I 型主动脉夹层修复后假腔持续存在(PFL)的原因之一。然而,关于这个重要问题的文章却很少。我们评估了 DANE 引起的 PFL 对长期结果的影响。

方法

122 例急性 I 型主动脉夹层患者于 2007 年 12 月行急诊手术。院内死亡率为 8%(10 例)。在幸存者中,93 例(平均年龄 67 岁)在术后 2 周内行增强 CT 检查。根据残余 FL 的情况,将这些患者分为 3 组:DANE 伴 PFL(n=19)、无 DANE 伴 PFL(n=27)和血栓形成的 FL(n=47)。分析降主动脉直径在早期和最后随访图像之间的变化。

结果

DANE 伴 PFL 组的主动脉生长速度大于其他 2 组(P<0.05)。DANE 伴 PFL 组在 5 年时出现远端主动脉夹层相关事件(66%)和远端主动脉病变扩大(62%)的无事件率较低。各组间晚期生存率无显著差异。DANE 伴 PFL 是远端主动脉事件的显著危险因素之一。

结论

急性 I 型主动脉夹层修复后 DANE 引起的 PFL 导致降主动脉扩张更大,是远端主动脉事件的显著危险因素之一。

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