El-Andari Ryaan, Moon Michael C
Division of Cardiac Surgery, Department of Surgery, University of Alberta, Edmonton, AB T6G 2R3, Canada.
J Cardiovasc Dev Dis. 2025 Jan 12;12(1):23. doi: 10.3390/jcdd12010023.
Acute type A aortic dissection (ATAAD) is a life-threatening condition that requires emergent surgical intervention. Numerous surgical approaches exist for ATAAD, and controversy remains regarding the optimal arch interventions for ATAAD patients. Aortic Arch Interventions: Approaches to ATAAD repair include hemiarch repair or extended arch repairs, including the hemiarch with a hybrid stent implantation, such as the AMDS hybrid Prosthesis, total arch replacement (TAR), and the use of an elephant trunk and frozen elephant trunk. While indications for each procedure exist, such as entry tears in the arch, arch aneurysms, and head vessel communications for TAR and malperfusion and a reduced risk of distal anastomotic new entry tears in Debakey I aortic dissection for the AMDS and frozen elephant trunks, the optimal intervention depends on numerous factors. Surgeon and center experience, resource availability, patient risk, and anatomy all contribute to the decision-making process. TAR has improved in safety over the years and has been demonstrated to be comparable to the hemiarch repair in terms of safety in many settings. TAR may also prevent adverse remodeling and can effectively treat more distal diseases, the presence of arch tears, arch aneurysms, and branch vessel involvement or malperfusion.
Numerous surgical approaches exist to manage ATAAD, allowing for the surgeon to tailor the repair to the individual patient and pathology. TAR allows for single or staged repair of extensive pathologies and can address distal entry tears, the aneurysmal arch, and head vessel pathologies. In cases with malperfusion, an AMDS can be used in many cases. The management strategy for ATAAD should always involve performing the best surgery for the patient, although in cases where a total arch is indicated but cannot be performed safely by a non-aortic surgeon, the safest approach may be to perform a hemiarch initially and to plan for an elective arch reoperation in the case it is required following close surveillance.
急性A型主动脉夹层(ATAAD)是一种危及生命的疾病,需要紧急手术干预。ATAAD有多种手术方法,对于ATAAD患者的最佳主动脉弓干预措施仍存在争议。
ATAAD修复方法包括半弓修复或扩大弓修复,其中半弓修复可采用混合支架植入,如AMDS混合假体,全弓置换(TAR),以及使用象鼻支架和冰冻象鼻支架。虽然每种手术都有其适应症,如TAR适用于主动脉弓入口撕裂、主动脉弓动脉瘤和头臂血管交通,以及灌注不良,而AMDS和冰冻象鼻支架适用于Debakey I型主动脉夹层中降低远端吻合口新入口撕裂的风险,但最佳干预措施取决于众多因素。外科医生和中心经验、资源可用性、患者风险和解剖结构都会影响决策过程。多年来,TAR的安全性有所提高,在许多情况下已被证明在安全性方面与半弓修复相当。TAR还可以防止不良重塑,并能有效治疗更多远端疾病、主动脉弓撕裂、主动脉弓动脉瘤以及分支血管受累或灌注不良。
存在多种手术方法来治疗ATAAD,使外科医生能够根据个体患者和病理情况定制修复方案。TAR可对广泛病变进行单次或分期修复,并可处理远端入口撕裂、动脉瘤性主动脉弓和头臂血管病变。在灌注不良的情况下,许多病例可使用AMDS。ATAAD的管理策略应始终包括为患者实施最佳手术,不过在需要进行全弓修复但非主动脉外科医生无法安全实施的情况下,最安全的方法可能是先进行半弓修复,并在密切监测后根据需要计划择期主动脉弓再次手术。