延缓衰老。

Slowing Down Aging.

机构信息

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

出版信息

Cell Metab. 2017 Oct 3;26(4):592-593. doi: 10.1016/j.cmet.2017.09.012.

DOI:10.1016/j.cmet.2017.09.012

Abstract

The hypothalamus plays a key role in coordinating the physiological changes that underlie mammalian aging. In a recent issue of Nature, Cai and colleagues (2017) shed new light on the mechanism of this effect by providing evidence that hypothalamic stem cells may regulate aging through the release of microRNAs in exosomes.

摘要

下丘脑在协调哺乳动物衰老的生理变化方面起着关键作用。在最近的一期《自然》杂志上，Cai 及其同事（2017 年）通过提供证据表明，下丘脑干细胞可能通过外泌体释放 microRNAs 来调节衰老，为这一效应的机制提供了新的线索。