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使用肱骨钉对成骨不全青少年的股骨进行手术重建。

Using humeral nail for surgical reconstruction of femur in adolescents with osteogenesis imperfecta.

作者信息

Sa-Ngasoongsong Paphon, Saisongcroh Tanyawat, Angsanuntsukh Chanika, Woratanarat Patarawan, Mulpruek Pornchai

机构信息

Department of Orthopedics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.

出版信息

World J Orthop. 2017 Sep 18;8(9):735-740. doi: 10.5312/wjo.v8.i9.735.

DOI:10.5312/wjo.v8.i9.735
PMID:28979858
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5605360/
Abstract

Osteogenesis imperfecta (OI) is a rare inherited connective tissue disorder caused by mutation of collagen which results in a wide spectrum of clinical manifestations including long bone fragility fractures and deformities. While the treatment for these fractures was recommended as using intramedullary fixation for minimizing stress concentration, the selection of the best implant in the adolescent OI patients for the surgical reconstruction of femur was still problematic, due to anatomy distortion and implant availability. We are reporting the surgical modification by using a humeral nail for femoral fixation in three adolescent OI patients with favorable outcomes.

摘要

成骨不全症（OI）是一种罕见的遗传性结缔组织疾病，由胶原蛋白突变引起，可导致广泛的临床表现，包括长骨脆性骨折和畸形。虽然对于这些骨折的治疗建议采用髓内固定以尽量减少应力集中，但由于解剖结构变形和植入物的可获得性，在青少年OI患者中选择最佳植入物进行股骨手术重建仍然存在问题。我们报告了在三名青少年OI患者中使用肱骨钉进行股骨固定的手术改良方法，取得了良好的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe6/5605360/db7af1b2f518/WJO-8-735-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe6/5605360/74cae94a6212/WJO-8-735-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe6/5605360/dff540cdc10f/WJO-8-735-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe6/5605360/15562774114b/WJO-8-735-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe6/5605360/0c06735b37c0/WJO-8-735-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe6/5605360/db7af1b2f518/WJO-8-735-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe6/5605360/74cae94a6212/WJO-8-735-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe6/5605360/dff540cdc10f/WJO-8-735-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe6/5605360/15562774114b/WJO-8-735-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe6/5605360/0c06735b37c0/WJO-8-735-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fe6/5605360/db7af1b2f518/WJO-8-735-g005.jpg

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本文引用的文献

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Orthopedics. 2017 Jan 1;40(1):e17-e22. doi: 10.3928/01477447-20161006-04. Epub 2016 Oct 13.
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Orthopaedic Considerations for the Adult With Osteogenesis Imperfecta.成骨不全成人的骨科考量
J Am Acad Orthop Surg. 2016 May;24(5):298-308. doi: 10.5435/JAAOS-D-15-00275.
3
Treatment of femoral shaft fracture with an interlocking humeral nail in older children and adolescents.儿童和青少年股骨干骨折采用交锁髓内钉治疗。
一只患有不明骨质疏松性骨病的猫采用多根髓内针治疗的长期随访
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Surgical Treatment of Bilateral Tibia Deformity in a 9-Year-Old Child Suffering from Osteogenesis Imperfecta Type III: A Case Report.一名9岁III型成骨不全患儿双侧胫骨畸形的手术治疗：病例报告
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Yonsei Med J. 2012 Mar;53(2):408-15. doi: 10.3349/ymj.2012.53.2.408.
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Bone mineral density and fracture rate in response to intravenous and oral bisphosphonates in adult osteogenesis imperfecta.成骨不全症患者静脉和口服双膦酸盐治疗后的骨密度和骨折率。
Calcif Tissue Int. 2010 Aug;87(2):120-9. doi: 10.1007/s00223-010-9383-y. Epub 2010 Jun 11.
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Osteogenesis imperfecta: diagnosis and treatment.成骨不全症：诊断与治疗
J Am Acad Orthop Surg. 2008 Jun;16(6):356-66. doi: 10.5435/00124635-200806000-00008.
6
Surgical treatment of osteogenesis imperfecta: current concepts.成骨不全症的外科治疗：当前概念
Curr Opin Pediatr. 2008 Feb;20(1):52-7. doi: 10.1097/MOP.0b013e3282f35f03.
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Bone plating in patients with type III osteogenesis imperfecta: results and complications.III型成骨不全患者的接骨板固定：结果与并发症
Iowa Orthop J. 2006;26:37-40.
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