Dadáková Eva, Brožová Kristýna, Piel Alex K, Stewart Fiona A, Modrý David, Celer Vladimír, Hrazdilová Kristýna
Department of Infectious Diseases and Microbiology, University of Veterinary and Pharmaceutical Sciences Brno, Palackého tř. 1946/1, 612 42, Brno, Czech Republic.
School of Natural Sciences and Psychology, Liverpool John Moores University, Byrum Street, Liverpool, L33AF, UK.
Arch Virol. 2018 Jan;163(1):191-196. doi: 10.1007/s00705-017-3576-x. Epub 2017 Oct 4.
Adenoviruses are a widespread cause of diverse human infections with recently confirmed zoonotic roots in African great apes. We focused on savanna-dwelling chimpanzees in the Issa Valley (Tanzania), which differ from those from forested sites in many aspects of behavior and ecology. PCR targeting the DNA polymerase gene detected AdV in 36.7% (69/188) of fecal samples. We detected five groups of strains belonging to the species Human mastadenovirus E and two distinct groups within the species Human mastadenovirus C based on partial hexon sequence. All detected AdVs from the Issa Valley are related to those from nearby Mahale and Gombe National Parks, suggesting chimpanzee movements and pathogen transmission.
腺病毒是人类多种感染的广泛病因，最近证实其在非洲大猩猩中存在人畜共患病根源。我们聚焦于坦桑尼亚伊萨山谷中生活在稀树草原的黑猩猩，它们在行为和生态的许多方面与森林地区的黑猩猩不同。针对DNA聚合酶基因的聚合酶链反应在36.7%（69/188）的粪便样本中检测到腺病毒。基于部分六邻体序列，我们检测到属于人类腺病毒E种的五组毒株以及人类腺病毒C种内两个不同的组。所有从伊萨山谷检测到的腺病毒都与附近马哈勒和贡贝国家公园的腺病毒有关，这表明黑猩猩的活动和病原体传播。
