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鉴定坦桑尼亚西部野生黑猩猩(Pan trogylodytes schweinfurthii)粪便标本中的腺病毒。

Identification of adenoviruses in fecal specimens from wild chimpanzees (Pan trogylodytes schweinfurthii) in western Tanzania.

机构信息

Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

出版信息

Am J Trop Med Hyg. 2010 May;82(5):967-70. doi: 10.4269/ajtmh.2010.09-0668.

Abstract

DNA of two distinctive adenoviruses was detected in wild chimpanzees in western Tanzania that showed clinical signs of acute, upper respiratory disease, notably coughing. The amplified sequences from part of the capsid hexon gene suggests that one virus is a novel adenovirus serotype candidate and the other virus is a species C adenovirus most closely related to recent isolates from captive chimpanzees in the United States, Simian AdV 37 with 86% nucleic acid identity and Simian AdV 40 with 95% nucleic acid identity, respectively. The species C adenovirus sequences suggest possible recombination with a human adenovirus. The source of these viruses and disease association is not known.

摘要

在坦桑尼亚西部出现急性呼吸道疾病(特别是咳嗽)临床症状的野生黑猩猩中,检测到两种独特的腺病毒 DNA。从衣壳六邻体基因的一部分扩增序列表明,一种病毒是一种新型腺病毒血清型候选病毒,另一种病毒是与最近在美国圈养黑猩猩中分离到的病毒关系最密切的 C 种腺病毒,即与猿猴腺病毒 37 的核酸同一性为 86%,与猿猴腺病毒 40 的核酸同一性为 95%。C 种腺病毒序列提示可能与人类腺病毒发生重组。这些病毒的来源和疾病关联性尚不清楚。

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