Hospital Universitario Nuestra Señora de Candelaria, Carretera Gral, Del Rosario, No. 145, 38010, Santa Cruz de Tenerife, Spain.
Instituto universitario de Integración en la Comunidad (INICO), University of Salamanca, Salamanca, Spain.
J Autism Dev Disord. 2018 Jan;48(1):239-250. doi: 10.1007/s10803-017-3328-5.
Since their separation as independent diagnostics, autism spectrum disorders (ASD) and schizophrenia spectrum disorders (SSD) have been conceptualized as mutually exclusive disorders. Similarities between both disorders can lead to misdiagnosis, especially when it comes to average-IQ adults who were not identified during childhood. The aim of this review was to examine the occurrence of SSD in average-IQ adults with ASD. Electronic and manual searches identified a total of 278 references, of which 10 were included in a meta-analysis. The pooled prevalence of SSD in the total ASD sample was close to 6%, pointing to a high co-occurrence of the two conditions. Further research is needed to determine the factors that predispose members of this population to the emergence of psychotic disorders.
自自闭症谱系障碍（ASD）和精神分裂谱系障碍（SSD）作为独立的诊断类别分离以来，它们一直被认为是相互排斥的疾病。这两种疾病之间的相似之处可能导致误诊，尤其是在那些没有在儿童时期被识别出的平均智商成年人中。本综述的目的是检查平均智商成年人中 ASD 伴发 SSD 的情况。电子和手动搜索共确定了 278 篇参考文献，其中 10 篇被纳入荟萃分析。在 ASD 总样本中，SSD 的总患病率接近 6%，表明这两种情况的高共病率。需要进一步的研究来确定导致这部分人群出现精神病性障碍的因素。
