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[海德堡视网膜断层扫描在青光眼早期诊断中的应用]

[Heidelberg retinal tomography of the optic disc in the early diagnosis of glaucoma].

作者信息

Machekhin V A, Fabrikantov O L

机构信息

Tambov branch of S. Fyodorov Eye Microsurgery Federal State Institution, 1 Rasskazovskoe shosse, Tambov, Russian Federation, 392000; Tambov State University named after G.R. Derzhavin, Medical Institute, 93 Sovetskaya St., Tambov, Russian Federation, 392000.

出版信息

Vestn Oftalmol. 2017;133(4):17-24. doi: 10.17116/oftalma2017133417-24.

DOI:10.17116/oftalma2017133417-24
PMID:28980561
Abstract

AIM

To analyze anatomical and topographic optic disc parameters with account to the disc area in glaucoma suspects.

MATERIAL AND METHODS

The study included 302 patients (408 eyes) aged 25 to 76 years (the mean age of 50.5±12.5 years); men and women roughly equal in number. The eyes were divided into 8 groups depending on the disc area, which ranged from 0.89 to 3.5 mm2. With HRT, 11 global and sector optic disc parameters were examined, 4 of which (disc area, rim area, cup/disc ratio, mean RNFL thickness) are presented in this paper.

RESULTS

The study revealed a great variability of disc area values as well as individual morphometric features of the examined optic discs. We have also established high statistical significance of the difference between the above-listed optic disc parameters, both global and sectoral, in groups with different disc areas with the exception of the mean RNFL thickness.

CONCLUSION

For early glaucoma detection with HRT, it is advisable to consider the individual area-dependent anatomical and topographic features of the optic disc.

摘要

目的

分析青光眼可疑患者视盘的解剖学和地形学参数,并考虑视盘面积。

材料与方法

该研究纳入了302例年龄在25至76岁之间(平均年龄为50.5±12.5岁)的患者(408只眼);男女数量大致相等。根据视盘面积将眼睛分为8组,视盘面积范围为0.89至3.5平方毫米。使用海德堡视网膜断层扫描仪(HRT)检查了11个整体和扇形视盘参数,本文呈现了其中4个参数(视盘面积、视盘边缘面积、杯盘比、视网膜神经纤维层平均厚度)。

结果

研究发现视盘面积值存在很大差异,以及所检查视盘的个体形态特征。我们还确定了在不同视盘面积组中,上述整体和扇形视盘参数之间差异具有高度统计学意义,但视网膜神经纤维层平均厚度除外。

结论

为了使用HRT早期检测青光眼,建议考虑视盘个体的面积依赖性解剖学和地形学特征。

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