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大健康挑战时代的团队科学与医学科学家

Team science and the physician-scientist in the age of grand health challenges.

作者信息

Steer Clifford J, Jackson Peter R, Hornbeak Hortencia, McKay Catherine K, Sriramarao P, Murtaugh Michael P

机构信息

Departments of Medicine and Genetics, Cell Biology, and Development, University of Minnesota Medical School, Minneapolis, Minnesota.

Division of Extramural Activities, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

出版信息

Ann N Y Acad Sci. 2017 Sep;1404(1):3-16. doi: 10.1111/nyas.13498.

DOI:10.1111/nyas.13498
PMID:28981971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5634532/
Abstract

Despite remarkable advances in medical research, clinicians face daunting challenges from new diseases, variations in patient responses to interventions, and increasing numbers of people with chronic health problems. The gap between biomedical research and unmet clinical needs can be addressed by highly talented interdisciplinary investigators focused on translational bench-to-bedside medicine. The training of talented physician-scientists comfortable with forming and participating in multidisciplinary teams that address complex health problems is a top national priority. Challenges, methods, and experiences associated with physician-scientist training and team building were explored at a workshop held at the Second International Conference on One Medicine One Science (iCOMOS 2016), April 24-27, 2016, in Minneapolis, Minnesota. A broad range of scientists, regulatory authorities, and health care experts determined that critical investments in interdisciplinary training are essential for the future of medicine and healthcare delivery. Physician-scientists trained in a broad, nonlinear, cross-disciplinary manner are and will be essential members of science teams in the new age of grand health challenges and the birth of precision medicine. Team science approaches have accomplished biomedical breakthroughs once considered impossible, and dedicated physician-scientists have been critical to these achievements. Together, they translate into the pillars of academic growth and success.

摘要

尽管医学研究取得了显著进展,但临床医生仍面临着来自新疾病、患者对干预措施反应的差异以及慢性健康问题患者数量不断增加等艰巨挑战。生物医学研究与未满足的临床需求之间的差距可以通过专注于转化医学(从实验室到临床)的高素质跨学科研究人员来弥合。培养有能力组建并参与解决复杂健康问题的多学科团队的优秀医师科学家是国家的首要任务。2016年4月24日至27日在明尼苏达州明尼阿波利斯举行的第二届“同一医学,同一科学”国际会议(iCOMOS 2016)上举办的一次研讨会上,探讨了与医师科学家培训和团队建设相关的挑战、方法和经验。众多科学家、监管机构和医疗保健专家一致认为,对跨学科培训进行关键投资对医学和医疗保健服务的未来至关重要。以广泛、非线性、跨学科方式培养的医师科学家过去是、将来也仍将是大健康挑战新时代和精准医学诞生之际科学团队的重要成员。团队科学方法取得了曾经被认为不可能的生物医学突破,而专注的医师科学家对这些成就至关重要。它们共同构成了学术成长与成功的支柱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bac/5634532/4a5d7ab3f6c6/nihms906173f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bac/5634532/4a5d7ab3f6c6/nihms906173f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bac/5634532/4a5d7ab3f6c6/nihms906173f1.jpg

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