Khanal Mahesh Kumar, Dhungana Raja Ram, Bhandari Pratiksha, Gurung Yadav, Paudel K N
Ministry of Health, Bheri Zonal Ayurveda Hospital, Surkhet, Nepal.
Nepal Public Health Foundation, Kathmandu, Nepal.
PLoS One. 2017 Oct 5;12(10):e0185806. doi: 10.1371/journal.pone.0185806. eCollection 2017.
Hypertension is one of the leading public health problems globally. About half of the deaths from cardiovascular diseases were attributed to hypertension in 2008. Reduction of blood pressure to normal range is one of the major challenges in preventing complications and future burden of cardiovascular diseases. Therefore, this study aims to determine prevalence, awareness, treatment and control of hypertension and its associated factors in Nepal.
This was a community based cross-sectional study conducted as a part of a community based intervention trial in Birendranagar Municipality of Surkhet district located at the Mid-western region of Nepal. We enrolled 1159 subjects aged 30 years and above. Out of 12 wards (administrative unit), four wards were selected randomly. Three hundred participants were recruited from each selected ward. Trained enumerator collected socio-demographic, anthropometric, and clinical data using standard STEPS questionnaires.
Out of all participants, women were 71% and mean age was 47±12.6 years. The overall prevalence of hypertension was 38.9% (95% CI: 36-41.7) while age and sex adjusted prevalence was 40.6%. The hypertension was present in 48.1% (95% CI: 45.2-50.9) of men and 35.2% (95% CI: 32.4-37.9)] of women. Male gender (OR = 1.49), older age (OR = 1.04 per year), Dalit caste (OR = 1.71), past history of cigarettes smoking (OR = 2.78), current alcohol consumption (OR = 1.75), and raised body mass index (OR = 1.17 per unit) were identified as significant factors associated with hypertension. Of total hypertensive respondents, 53.4% (95% CI: 48.7-58) were aware, 29% (95% CI: 24.8-33.1) were receiving treatment for high blood pressure, and 8.2% (95% CI: 5.6-10.7) had controlled blood pressure. The awareness, treatment, and control status were worse in younger participants.
The study revealed high prevalence with low awareness, treatment, and control of hypertension in Nepal. Gender, age, ethnicity, smoking, drinking alcohol, and body mass index were associated with hypertension. Immediate public health and individual measures are warranted to reduce future burden of cardiovascular diseases.
ClinicalTrial.gov (NCT02981251).
高血压是全球主要的公共卫生问题之一。2008年,约一半的心血管疾病死亡归因于高血压。将血压降至正常范围是预防心血管疾病并发症和未来负担的主要挑战之一。因此,本研究旨在确定尼泊尔高血压的患病率、知晓率、治疗率、控制率及其相关因素。
这是一项基于社区的横断面研究,作为尼泊尔中西部地区苏尔凯特县比伦德拉纳加尔市一项基于社区的干预试验的一部分。我们纳入了1159名30岁及以上的受试者。在12个 wards(行政单位)中,随机选择了4个wards。从每个选定的wards招募300名参与者。经过培训的调查员使用标准的STEPS问卷收集社会人口统计学、人体测量学和临床数据。
在所有参与者中,女性占71%,平均年龄为47±12.6岁。高血压的总体患病率为38.9%(95%可信区间:36 - 41.7),而年龄和性别调整后的患病率为40.6%。男性高血压患病率为48.1%(95%可信区间:45.2 - 50.9),女性为35.2%(95%可信区间:32.4 - 37.9)。男性(比值比 = 1.49)、年龄较大(每年比值比 = 1.04)、达利特种姓(比值比 = 1.71)、既往吸烟史(比值比 = 2.78)、当前饮酒(比值比 = 1.75)和体重指数升高(每单位比值比 = 1.17)被确定为与高血压相关的显著因素。在所有高血压受访者中,53.4%(95%可信区间:48.7 - 58)知晓自己患有高血压,29%(95%可信区间:24.8 - 33.1)正在接受高血压治疗,8.2%(95%可信区间:5.6 - 10.7)血压得到控制。年轻参与者的知晓率、治疗率和控制率更差。
该研究表明尼泊尔高血压患病率高,但知晓率、治疗率和控制率低。性别、年龄、种族、吸烟、饮酒和体重指数与高血压有关。需要立即采取公共卫生和个人措施,以减轻未来心血管疾病的负担。
ClinicalTrial.gov(NCT02981251)