Kulothungan Vaitheeswaran, Seenappa Kavyashree, Mohan Rohith
Indian Council of Medical Research - National Centre for Disease Informatics and Research, Nirmal Bhawan-ICMR Complex (II Floor), Poojanahalli, Kannamangala Post, Bengaluru, Karnataka, 562110, India.
J Hum Hypertens. 2025 Jul 9. doi: 10.1038/s41371-025-01039-z.
Hypertension, a leading cause of cardiovascular diseases, accounts for 7.5 million deaths annually, affecting over 1.3 billion people globally, with significant burdens in low- and middle-income countries like India. It significantly impacts India's population, with low rates of awareness, diagnosis, and treatment. This study examines the hypertension care cascade and its key determinants at the national, state, and district levels in India. The analysis was conducted using data from the NFHS-5 survey, involving a total of 743,067 adults aged 18-54 years. From this group, 118,231 individuals with hypertension were identified, and the hypertension care cascade was constructed. A color-coded map was generated to visually depict geographic disparities in prevalence rates across different regions of India. Multivariate logistic regression was employed at the district, state, and national levels, with significance set at p < 0.05. Hypertension awareness varied significantly across districts, with an average rate of 46.0%, ranging from 89.6-6.1%. Treatment rates were 18.7%, with considerable disparity among districts. Blood pressure control was achieved in 32.9% of individuals with hypertension. Older age, female gender, higher socioeconomic status, urban residence, and obesity were associated with better attainment of cascade steps. Conversely, younger age and alcohol consumption were linked to lower attainment, while educated individuals showed lower treatment-seeking behavior despite better awareness. Poor-performing districts were identified in Gujarat, Chhattisgarh, and Madhya Pradesh. These findings highlight the need for targeted, evidence-based interventions to address regional disparities, enhance hypertension care, and reduce the cardiovascular disease burden in India.
高血压是心血管疾病的主要病因,每年导致750万人死亡,全球超过13亿人受其影响,在印度等低收入和中等收入国家负担沉重。它对印度人口产生了重大影响,人们对高血压的知晓率、诊断率和治疗率较低。本研究考察了印度国家、邦和地区层面的高血压照护流程及其关键决定因素。分析使用了全国第五次家庭健康调查(NFHS - 5)的数据,共涉及743,067名18至54岁的成年人。从这个群体中,识别出118,231名高血压患者,并构建了高血压照护流程。生成了一张彩色编码地图,直观地描绘印度不同地区患病率的地理差异。在地区、邦和国家层面采用多变量逻辑回归分析,显著性设定为p < 0.05。不同地区的高血压知晓率差异显著,平均知晓率为46.0%,范围在89.6%至6.1%之间。治疗率为18.7%,各地区之间存在相当大的差异。32.9%的高血压患者实现了血压控制。年龄较大、女性、社会经济地位较高、居住在城市以及肥胖与更好地完成照护流程步骤相关。相反,年龄较小和饮酒与较低的完成率相关,而受过教育的人尽管知晓率较高,但寻求治疗的行为较低。古吉拉特邦、恰蒂斯加尔邦和中央邦被确定为表现较差的地区。这些发现凸显了需要有针对性的、基于证据的干预措施,以解决地区差异,加强高血压照护,并减轻印度的心血管疾病负担。