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辐射诱发的恶性肿瘤:放疗成为“双刃剑”——文献综述

Radiation-Induced Malignancies Making Radiotherapy a "Two-Edged Sword": A Review of Literature.

作者信息

Singh Gunjesh Kumar, Yadav Vikas, Singh Pragya, Bhowmik K T

机构信息

Department of Radiotherapy, VMMC & Safdarjung Hospital, New Delhi 110029, India.

Department of Pathology, VMMC & Safdarjung Hospital, New Delhi 110029, India.

出版信息

World J Oncol. 2017 Feb;8(1):1-6. doi: 10.14740/wjon996w. Epub 2017 Feb 23.

Abstract

Radiotherapy is one of the modalities of treatment of malignancies. Radiation-induced malignancies (RIMs) are late complications of radiotherapy, seen among the survivors of both adult and pediatric cancers. Mutagenesis of normal tissues is the basis for RIMs. The aim of this review of literature was to discuss epidemiology, factors affecting and different settings in which RIM occur.

摘要

放射治疗是恶性肿瘤的治疗方式之一。辐射诱发的恶性肿瘤(RIMs)是放射治疗的晚期并发症,见于成人和儿童癌症的幸存者中。正常组织的诱变是RIMs的基础。这篇文献综述的目的是讨论RIMs的流行病学、影响因素和发生的不同情况。

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