Badeli Hamidreza, Dalili Hossein, Rad Afagh Hassanzadeh, Medghalchi Abdolreza, Dalili Setila, Koohmanaee Shahin
Pediatric Growth Disorders Research Center, 17 Shahrivar Hospital, School of Medicine, Guilan University of Medical Sciences, Guilan, Iran.
Department of Pediatrics, Breastfeeding Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Int J Prev Med. 2017 Sep 14;8:72. doi: 10.4103/ijpvm.IJPVM_48_16. eCollection 2017.
A large number of epidemiological studies from different geographical regions showed a considerable relationship between low birth weight (LBW) and adverse health effects later in life. This study aims to assess the birth weight (BW) as a cardio metabolic risk factor in Iranian adolescents.
This cross-sectional study was conducted on 12-year-old students from different areas of Rasht, North Iran. Data were collected by a questionnaire including variables as birth height, BW, gestational age, blood pressure, and laboratory tests including triglycerides (TGs), total cholesterol, low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), and insulin level. Data were analyzed using -test, Chi-square, and Pearson correlation coefficient.
Overall, 858 adolescents participated in this study. Results showed significant correlation between BW and abdominal circumference, hip circumference, total cholesterol, TG, HDL-C and LDL-C ( = 0.064, 0.194, 0.224, 0.017, and 0.017, respectively).
The study findings on the correlation between BW and cardio metabolic factors might serve as confirmatory evidence on the association of LBW with future cardio metabolic disorders.
来自不同地理区域的大量流行病学研究表明，低出生体重（LBW）与日后的不良健康影响之间存在相当大的关联。本研究旨在评估出生体重（BW）作为伊朗青少年心血管代谢风险因素的情况。
这项横断面研究针对来自伊朗北部拉什特不同地区的12岁学生进行。通过问卷调查收集数据，问卷包括出生身高、BW、孕周、血压等变量，以及甘油三酯（TGs）、总胆固醇、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）和胰岛素水平等实验室检查数据。使用t检验、卡方检验和皮尔逊相关系数进行数据分析。
总体而言，858名青少年参与了本研究。结果显示BW与腹围、臀围、总胆固醇、TG、HDL-C和LDL-C之间存在显著相关性（分别为=0.064、0.194、0.224、0.017和0.017）。
关于BW与心血管代谢因素之间相关性的研究结果可能为LBW与未来心血管代谢紊乱之间的关联提供确证证据。
