Dalili Setila, Mohammadi Hamid, Rezvany Seyed Mahmood, Dadashi Arsalan, Novin Mohammad Hassan, Gholaminejad Hajar, Medghalchi Abdolreza, Mohtasham Amiri Zahra, Dalili Hossein, Hassanzadeh Rad Afagh
Department of Pediatric Endocrinology, Pediatric Growth Disorders Research Center, 17 Shahrivar Hospital, School of Medicine, Guilan University of Medical Sciences, Guilan, Iran.
Indian J Pediatr. 2015 May;82(5):445-9. doi: 10.1007/s12098-014-1573-6. Epub 2014 Sep 25.
To investigate the relationship between blood pressure, anthropometric indices and metabolic profile in adolescents.
The present cross sectional study was conducted in 1005, 12-y-old junior students referred to 15 urban health centers of Rasht. Samples were recruited randomly and data were collected in a form which consisted of demographic characteristics, history of disease in samples and their immediate families, birth weight, physical examination and clinical examination including height, weight, blood pressure and body mass index. Also, metabolic profiles including fasting blood sugar (FBS), blood sugar (BS), cholesterol, and triglyceride (TG), low density lipoprotein (LDL), high-density lipoprotein (HDL) and insulin levels were measured. Data were analyzed in SPSS software, by descriptive and analytic statistics and p value 0.05 was considered statistically significant.
Eight hundred fifty nine adolescents consisting of 550 (64 %) boys and 309 (34 %) girls participated in this study; 11.4 % (84/739 cases) of the participants had hypertension. The strongest correlation was seen between systolic blood pressure and weight, waist or hip circumferences and insulin levels. Also, FBS had very weak correlation with blood pressure.
Thus, weight, waist and hip circumferences, insulin levels, high TG and low HDL have been indicated as the strongest correlating factors for high blood pressure.Thus, these factors should be investigated in high risk children and followed in hypertensive child to monitor cardiometabolic risk factors.
探讨青少年血压、人体测量指标与代谢谱之间的关系。
本横断面研究在拉什特市15个城市健康中心的1005名12岁初中生中进行。样本随机选取，数据通过一份表格收集，内容包括人口统计学特征、样本及其直系亲属的疾病史、出生体重、体格检查和临床检查，包括身高、体重、血压和体重指数。此外，还测量了代谢谱，包括空腹血糖（FBS）、血糖（BS）、胆固醇、甘油三酯（TG）、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）和胰岛素水平。数据在SPSS软件中进行分析，采用描述性和分析性统计方法，p值<0.05被认为具有统计学意义。
859名青少年参与了本研究，其中包括550名（64%）男孩和309名（34%）女孩；11.4%（84/739例）的参与者患有高血压。收缩压与体重、腰围或臀围以及胰岛素水平之间的相关性最强。此外，FBS与血压的相关性非常弱。
因此，体重、腰围和臀围、胰岛素水平、高TG和低HDL被认为是高血压的最强相关因素。因此，应在高危儿童中对这些因素进行调查，并对高血压儿童进行跟踪，以监测心脏代谢危险因素。
