中国犬类中首次检测到猪圆环病毒3型。
First molecular detection of porcine circovirus type 3 in dogs in China.
作者信息
Zhang Jiaxin, Liu Zhenguo, Zou Yawen, Zhang Nanxiangzi, Wang Dongliang, Tu Di, Yang Linchen, Deng Zhibang, Yang Yi, Jiang Ping, Wang Naidong
机构信息
Research Center of Reverse Vaccinology (RCRV) and Laboratory of Functional Proteomics (LFP), College of Veterinary Medicine, Hunan Agricultural University, Changsha, 410128, China.
Department of Infectious Disease, the Third Xiangya Hospital of Central South University, Changsha, 410013, China.
出版信息
Virus Genes. 2018 Feb;54(1):140-144. doi: 10.1007/s11262-017-1509-0. Epub 2017 Oct 5.
Porcine circovirus type 3 (PCV3) has recently been isolated from diseased pigs within the USA. The objective was to detect the presence of PCV3 in dogs. Nested polymerase chain reactions (PCR) with PCV3-specific primers for the capsid gene were used to detect PCV3 genomic DNA in serum samples from dogs (n = 44) in China. There was PCV3 DNA detected in 4 of 44 dogs [all were negative for PCV2 and canine circovirus (CanineCV)]. Based on sequence analysis, positive sequences were grouped into PCV3 genotypes. However, these isolates had close evolutionary relationships with FoxCV (KP941114) and CanineCV (JQ821392). Further investigations of the epidemiology, evolutionary biology, and pathobiology of PCV3 to dogs are warranted.
猪圆环病毒3型（PCV3）最近已在美国的患病猪中分离出来。目的是检测犬体内PCV3的存在情况。使用针对衣壳基因的PCV3特异性引物进行巢式聚合酶链反应（PCR），以检测来自中国44只犬血清样本中的PCV3基因组DNA。44只犬中有4只检测到PCV3 DNA [所有犬对PCV2和犬圆环病毒（CanineCV）均为阴性]。基于序列分析，阳性序列被分为PCV3基因型。然而，这些分离株与狐圆环病毒（FoxCV，KP941114）和犬圆环病毒（CanineCV，JQ821392）具有密切的进化关系。有必要对PCV3在犬中的流行病学、进化生物学和病理生物学进行进一步研究。
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