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中国结直肠癌的治疗现状:一项系统综述

The current status of treatment for colorectal cancer in China: A systematic review.

作者信息

Zhang Yumei, Chen Zhiyu, Li Jin

机构信息

Department of VIP Clinic, Tongji University South Branch of Shanghai East Hospital Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai Medical College Department of Oncology, Tongji University Shanghai East Hospital, Shanghai, China.

出版信息

Medicine (Baltimore). 2017 Oct;96(40):e8242. doi: 10.1097/MD.0000000000008242.

DOI:10.1097/MD.0000000000008242
PMID:28984783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5738019/
Abstract

BACKGROUND

Colorectal cancer (CRC) is one of the most common cancers all over the world, but its epidemiology is obviously different in various regions.

METHODS

The treatment of CRC also has varying characteristics due to differences in economy, geography, disease onset, chemotherapy, and other factors, although international guidelines are used to guide the treatment of CRC in China.

RESULTS

This paper summarizes the current status of CRC treatment, including surgical therapy, neoadjuvant radiotherapy and chemotherapy, postoperative chemotherapy, targeted therapy, maintenance therapy, and immunotherapy, according to the clinical situation in China, so as to provide better therapy and improve clinical practice for patients with CRC.

CONCLUSION

This research shows that the treatment of colorectal cancer continues to progress, and the patient's efficacy and quality of life have improved.

摘要

背景

结直肠癌(CRC)是全球最常见的癌症之一,但其流行病学在不同地区存在明显差异。

方法

尽管中国采用国际指南指导结直肠癌的治疗,但由于经济、地理、疾病发病情况、化疗等因素的差异,结直肠癌的治疗也具有不同特点。

结果

本文根据中国的临床情况,总结了结直肠癌治疗的现状,包括手术治疗、新辅助放疗和化疗、术后化疗、靶向治疗、维持治疗和免疫治疗,以便为结直肠癌患者提供更好的治疗并改善临床实践。

结论

本研究表明,结直肠癌的治疗不断进步,患者的疗效和生活质量得到了提高。

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本文引用的文献

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Front Immunol. 2017 May 26;8:619. doi: 10.3389/fimmu.2017.00619. eCollection 2017.
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Right- vs. Left-Sided Metastatic Colorectal Cancer: Differences in Tumor Biology and Bevacizumab Efficacy.右侧与左侧转移性结直肠癌:肿瘤生物学及贝伐单抗疗效的差异
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Trends and Outcomes of Surgical Treatment for Colorectal Cancer between 2004 and 2012- an Analysis using National Inpatient Database.2004 年至 2012 年期间,使用国家住院患者数据库分析结直肠癌的手术治疗趋势和结果。
Sci Rep. 2017 May 17;7(1):2006. doi: 10.1038/s41598-017-02224-y.
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Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomized trials.在六个随机试验中,接受化疗和 EGFR 靶向抗体治疗的 RAS 野生型转移性结直肠癌患者中,原发肿瘤侧的预后和预测价值。
Ann Oncol. 2017 Aug 1;28(8):1713-1729. doi: 10.1093/annonc/mdx175.
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