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局灶性脑病变情况下静息态功能磁共振成像的局限性

Limitations of Resting-State Functional MR Imaging in the Setting of Focal Brain Lesions.

作者信息

Agarwal Shruti, Sair Haris I, Pillai Jay J

机构信息

Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Phipps B-100, 1800 Orleans Street, Baltimore, MD 21287, USA.

Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Phipps B-100, 1800 Orleans Street, Baltimore, MD 21287, USA.

出版信息

Neuroimaging Clin N Am. 2017 Nov;27(4):645-661. doi: 10.1016/j.nic.2017.06.004.

Abstract

Methods of image acquisition and analysis for resting-state functional MR imaging (rsfMR imaging) are still evolving. Neurovascular uncoupling and susceptibility artifact are important confounds of rsfMR imaging in the setting of focal brain lesions such as brain tumors. This article reviews the detection of these confounds using rsfMR imaging metrics in the setting of focal brain lesions. In the near future, with the wide range of ongoing research in rsfMR imaging, these issues likely will be overcome and will open new windows into brain function and connectivity.

摘要

静息态功能磁共振成像(rsfMR成像)的图像采集和分析方法仍在不断发展。在脑肿瘤等局灶性脑病变的情况下,神经血管解偶联和磁化率伪影是rsfMR成像的重要混杂因素。本文综述了在局灶性脑病变情况下使用rsfMR成像指标检测这些混杂因素的方法。在不久的将来,随着rsfMR成像领域正在进行的广泛研究,这些问题可能会得到解决,并将为脑功能和连通性打开新的窗口。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc1e/5661980/39dd0c68599e/nihms887644f1.jpg

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