Ejtahed Hanieh-Sadat, Hasani-Ranjbar Shirin, Larijani Bagher
Altern Ther Health Med. 2017 Nov;23(6):8-9.
Personalized medicine is an approach for medical decisions, practices, and interventions that considers individual variations in genes, environment, and lifestyle for each person. Regarding complex metabolic patterns associated with different diseases, characterizing unique metabolic patterns of each patient seems like a practical approach. We can imagine a future in which routinely analyzing the microbiome allows us to predict individualized responses to different foods and drugs. Microbiome analysis of individuals may be added to future routine personalized medicine protocols after comparing the costs and benefits of microbiome-sequencing technology. Moreover, improved understanding of the human microbiome could lead to the development of novel therapeutic strategies for different diseases. Potential therapeutic agents, such as personalized probiotic and prebiotic supplements, dietary interventions, and fecal microbiota transplantation that can be used to reshape the gut microbiome, represent a reasonable strategy in an era of personalized medicine.
个性化医疗是一种用于医疗决策、实践和干预的方法，它考虑了每个人在基因、环境和生活方式方面的个体差异。对于与不同疾病相关的复杂代谢模式，表征每个患者独特的代谢模式似乎是一种切实可行的方法。我们可以设想这样一个未来，即常规分析微生物组能让我们预测个体对不同食物和药物的反应。在比较微生物组测序技术的成本和效益之后，个体的微生物组分析可能会被纳入未来的常规个性化医疗方案中。此外，对人类微生物组的深入了解可能会促成针对不同疾病的新型治疗策略的开发。潜在的治疗剂，如可用于重塑肠道微生物组的个性化益生菌和益生元补充剂、饮食干预措施以及粪便微生物群移植，在个性化医疗时代是一种合理的策略。
