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关于低强度激光疗法对慢性疼痛和骨关节炎非药物性疼痛控制益处的文献综述。

Review of Literature on Low-level Laser Therapy Benefits for Nonpharmacological Pain Control in Chronic Pain and Osteoarthritis.

作者信息

Dima Robert, Tieppo Francio Vinicius, Towery Chris, Davani Saied

出版信息

Altern Ther Health Med. 2018 Sep;24(5):8-10.

PMID:28987080
Abstract

INTRODUCTION

Low-level laser therapy (LLLT) is a form of light therapy that triggers biochemical changes within cells. Photons are absorbed by cellular photoreceptors, triggering chemical alterations and potential biochemical benefits to the human body. LLLT has been used in pain management for years and is also known as cold laser therapy, which uses low-frequency continuous laser of typically 600 to 1000 nm wavelength for pain reduction and healing stimulation. Many studies have demonstrated analgesic and anti-inflammatory effects provided by photobiomodulation in both experimental and clinical trials.

OBJECTIVE

The purpose of this research article was to present a summary of the possible pain management benefits of LLLT.

RESULTS

In cold laser therapy, coherent light of wavelength 600 to 1000 nm is applied to an area of concern with hope for photo-stimulating the tissues in a way that promotes and accelerates healing. This is evidenced by the similarity in absorption spectra between oxidized cytochrome c oxidase and action spectra from biological responses to light. LLLT, using the properties of coherent light, has been seen to produce pain relief and fibroblastic regeneration in clinical trials and laboratory experiments. LLLT has also been seen to significantly reduce pain in the acute setting; it is proposed that LLLT is able to reduce pain by lowering the level of biochemical markers and oxidative stress, and the formation of edema and hemorrhage. Many studies have demonstrated analgesic and anti-inflammatory effects provided by photobiomodulation in both experimental and clinical trials.

CONCLUSION

Based on current research, the utilization of LLLT for pain management and osteoarthritic conditions may be a complementary strategy used in clinical practice to provide symptom management for patients suffering from osteoarthritis and chronic pain.

摘要

引言

低强度激光疗法(LLLT)是一种光疗法,可引发细胞内的生化变化。光子被细胞光感受器吸收,引发化学改变并给人体带来潜在的生化益处。LLLT已用于疼痛管理多年,也被称为冷激光疗法,它使用波长通常为600至1000纳米的低频连续激光来减轻疼痛和刺激愈合。许多研究已在实验和临床试验中证明了光生物调节的镇痛和抗炎作用。

目的

本文的目的是总结LLLT在疼痛管理方面可能带来的益处。

结果

在冷激光疗法中,将波长为600至1000纳米的相干光照射到关注区域,希望以促进和加速愈合的方式对组织进行光刺激。氧化细胞色素c氧化酶的吸收光谱与生物对光反应的作用光谱之间的相似性证明了这一点。在临床试验和实验室实验中,利用相干光特性的LLLT已被证明可减轻疼痛并促进成纤维细胞再生。LLLT在急性情况下也能显著减轻疼痛;有人提出LLLT能够通过降低生化标志物水平和氧化应激以及减少水肿和出血的形成来减轻疼痛。许多研究已在实验和临床试验中证明了光生物调节的镇痛和抗炎作用。

结论

基于目前的研究,将LLLT用于疼痛管理和骨关节炎病症可能是临床实践中用于为骨关节炎和慢性疼痛患者提供症状管理的一种补充策略。

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