计算扩散加权磁共振成像在胰腺腺癌中的可视化：与获得的扩散加权成像的比较。
Computed diffusion-weighted MR imaging for visualization of pancreatic adenocarcinoma: Comparison with acquired diffusion-weighted imaging.
机构信息
Department of Radiology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima City 890-8544, Japan.
Department of Radiology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima City 890-8544, Japan.
出版信息
Eur J Radiol. 2017 Oct;95:39-45. doi: 10.1016/j.ejrad.2017.07.022. Epub 2017 Jul 29.
OBJECTIVE
To assess the feasibility of computed diffusion-weighted imaging (cDWI) in comparison with directly acquired DWI for visualizing pancreatic adenocarcinomas.
MATERIALS AND METHODS
Patients with pancreatic adenocarcinoma underwent DWI at b-values of 0, 1000 (DWI), 1500 (DWI) and 2000 (DWI) s/mm. From DWIs at b-values of 0 and 1000s/mm, we generated cDWIs at b-values of 1500 (cDWI) and 2000 (cDWI) s/mm. DWI findings of pancreatic adenocarcinomas (clear hyperintensity; hyperintensity with an unclear distal border; and isointensity), the image quality and the tumor to pancreas contrast ratio (CR) were compared between directly acquired DWI and cDWI.
RESULTS
Among the 63 included patients, clear hyperintense tumors were seen in 35 on DWI, 50 on DWI, 50 on cDWI, 53 on DWI and 44 on cDWI. Incidence of clear hyperintense tumors was significantly higher on cDWI than on DWI (P=0.013). There was no significant difference in the incidence of clear hyperintense tumors between DWI and cDWI (P>0.999), but a lower incidence was seen on cDWI than on DWI (P=0.028). Image quality was lower on cDWI than on DWI at b-values of 1500 (P=0.002) and 2000s/mm (P<0.001). The tumor to distal pancreas CR was significantly higher on cDWI than on cDWI (P<0.001), and on cDWI than on DWI (P<0.001). The cDWI showed a significantly higher tumor to distal pancreas CR than DWI at b-values of 1500 (P=0.004) and 2000s/mm (P<0.001).
CONCLUSIONS
cDWI generated from b-values of 0 and 1000s/mm should be considered more effective than DWI and at least as effective as DWI.
目的
评估计算扩散加权成像（cDWI）与直接采集 DWI 相比在显示胰腺腺癌中的可行性。
材料和方法
对胰腺腺癌患者行 b 值为 0、1000（DWI）、1500（DWI）和 2000（DWI）s/mm 的 DWI。从 b 值为 0 和 1000s/mm 的 DWIs 中，我们生成 b 值为 1500（cDWI）和 2000（cDWI）s/mm 的 cDWIs。比较胰腺腺癌的 DWI 表现（明显高信号；边界不清的高信号；等信号）、图像质量和肿瘤与胰腺的对比率（CR），直接采集的 DWI 和 cDWI 之间。
结果
在 63 名纳入的患者中，35 名患者在 DWI 上表现为明显高信号肿瘤，50 名患者在 DWI 上，50 名患者在 cDWI 上，53 名患者在 DWI 上，44 名患者在 cDWI 上。cDWI 上明显高信号肿瘤的发生率明显高于 DWI（P=0.013）。DWI 和 cDWI 之间明显高信号肿瘤的发生率无差异（P>0.999），但 cDWI 上的发生率较低（P=0.028）。cDWI 的图像质量低于 DWI 的 b 值为 1500（P=0.002）和 2000s/mm（P<0.001）。cDWI 的肿瘤与远端胰腺 CR 明显高于 cDWI（P<0.001）和 cDWI（P<0.001）。cDWI 在 b 值为 1500（P=0.004）和 2000s/mm（P<0.001）时，肿瘤与远端胰腺 CR 明显高于 DWI。
结论
从 b 值为 0 和 1000s/mm 生成的 cDWI 应被认为比 DWI 更有效，并且至少与 DWI 一样有效。
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