Yoshida Tsukasa, Urikura Atsushi, Nakashima Kazuaki, Kawashima Ippei, Endo Masahiro
Department of Diagnostic Radiology, Shizuoka Cancer Center, Shizuoka, Japan.
Graduate School of Health Sciences, Ibaraki Prefectural University of Health Sciences, Ibaraki, Japan.
Abdom Radiol (NY). 2025 Sep 12. doi: 10.1007/s00261-025-05198-y.
To investigate the agreement in apparent diffusion coefficient (ADC) values and the image quality of abdominal computed diffusion-weighted imaging (cDWI) generated by two software programs.
This retrospective study included 154 patients (64 males, 90 females; mean age: 70.1 ± 10.7 years) who underwent abdominal diffusion-weighted imaging (DWI) between November 2023 and October 2024. DWI was acquired with a b = 0 and 1000 s/mm using a 3.0T scanner. cDWIs with b 1500 and 2000 were generated by a scanner console software and a commercially available software program. The ADC and signal-to-noise ratio (SNR) were measured in normal tissues. The contrast-to-noise ratio (CNR) of normal tissues relative to the paraspinal muscle was also measured. Agreement and reliability of ADC value were assessed using Bland-Altman analysis and intraclass correlation coefficients (ICC), respectively. SNR and CNR were compared using paired t-tests.
ADC bias and limits of agreement ranged from - 0.2 to 0.7% and 0.3-2.1%, respectively. ICCs for ADC values ranged within 0.991 and 1.000 (p < 0.05) for all tissues. Significant SNR differences were observed in b1500 (liver, spleen, kidney) and b2000 (liver, bile). Significant CNR differences were noted in b1500 (liver, pancreas, kidney) and b2000 (excluding spleen).
There is strong agreement and high reliability in ADC values between the two software programs. Although significant differences in SNR and CNR were observed, their clinical impact appears minimal. These findings indicate that the ADC values and image quality of cDWI are consistent between the two software programs.
研究两种软件程序生成的腹部计算机扩散加权成像（cDWI）的表观扩散系数（ADC）值及图像质量的一致性。
这项回顾性研究纳入了2023年11月至2024年10月期间接受腹部扩散加权成像（DWI）的154例患者（64例男性，90例女性；平均年龄：70.1±10.7岁）。使用3.0T扫描仪在b = 0和1000 s/mm²条件下采集DWI。由扫描仪控制台软件和一款商用软件程序生成b值为1500和2000的cDWI。在正常组织中测量ADC和信噪比（SNR）。还测量了正常组织相对于椎旁肌的对比噪声比（CNR）。分别使用Bland-Altman分析和组内相关系数（ICC）评估ADC值的一致性和可靠性。使用配对t检验比较SNR和CNR。
ADC偏差和一致性界限分别为-0.2%至0.7%和0.3%至2.1%。所有组织的ADC值的ICC在0.991至1.000范围内（p < 0.05）。在b1500（肝脏、脾脏、肾脏）和b2000（肝脏、胆汁）中观察到显著的SNR差异。在b1500（肝脏、胰腺、肾脏）和b2000（不包括脾脏）中注意到显著的CNR差异。
两种软件程序之间的ADC值具有高度一致性和高可靠性。尽管观察到SNR和CNR存在显著差异，但其临床影响似乎最小。这些发现表明两种软件程序生成的cDWI的ADC值和图像质量是一致的。
