Bhasin Vinny, Singh Madhavi, Goutam Manish, Singh Shuchi, Nigam Adamya S, Joshi Aditya
Department of Orthodontics and Dentofacial Orthopaedics Hitkarini Dental College & Hospital, Jabalpur, Madhya Pradesh India, Phone: +919501544877, e-mail:
Dentica Oral Care and Implant Centre Ranchi, Jharkhand India.
J Contemp Dent Pract. 2017 Oct 1;18(10):977-980. doi: 10.5005/jp-journals-10024-2159.
There exist a number of factors that affect the outcome of orthodontic treatment. These factors can be assessed by various gingival markers. One such maker is myeloperoxidase (MPO). Hence, we planned the present study to assess and compare the MPO activity in the gingival crevicular fluid (GCF) of subjects undergoing orthodontic treatment by different aligning arch wires.
The present study included assessment of patients who underwent orthodontic treatment for crowding of anterior teeth. Diagnostic cast models of all the subjects were made for recording the irregularity index. All the subjects were randomly divided into three study groups with 15 patients in each group based on the type of nickel-titanium (NiTi) arch wires used. A collection of GCF samples was done in all the patients at various time intervals and it was sent to the laboratory for assessment of MPO activity. Activity of the MPO enzyme was expressed in terms of number of units per 100 μL. All the results obtained were compiled and analyzed by Statistical Package for the Social Sciences (SPSS) software.
We observed that nonsignificant results were obtained while comparing the mean age and mean gingival score in all the study groups. However, significant results were obtained on comparing the mean MPO enzymatic activity in all the study groups at different time intervals.
Both superelastic NiTi and heat-activated NiTi generate optimal forces, which are necessary for higher metabolic response of the periodontal ligament.
In the intimal stages of orthodontic treatment, both superelastic NiTi and heat-activated NiTi wires are superior in leveling and aligning the crowded teeth.
存在许多影响正畸治疗结果的因素。这些因素可通过各种牙龈标志物进行评估。髓过氧化物酶（MPO）就是这样一种标志物。因此，我们计划开展本研究，以评估和比较使用不同矫治弓丝的正畸治疗患者龈沟液（GCF）中的MPO活性。
本研究纳入了因前牙拥挤接受正畸治疗的患者。制作了所有受试者的诊断石膏模型以记录不规则指数。根据所使用的镍钛（NiTi）弓丝类型，将所有受试者随机分为三个研究组，每组15例患者。在不同时间间隔对所有患者采集GCF样本，并将其送至实验室评估MPO活性。MPO酶的活性以每100μL的单位数表示。所有获得的结果由社会科学统计软件包（SPSS）进行汇总和分析。
我们观察到，在比较所有研究组的平均年龄和平均牙龈评分时，结果无统计学意义。然而，在比较所有研究组在不同时间间隔的平均MPO酶活性时，结果具有统计学意义。
超弹性NiTi和热激活NiTi均能产生最佳力，这对于牙周膜的更高代谢反应是必需的。
在正畸治疗的初始阶段，超弹性NiTi丝和热激活NiTi丝在排齐拥挤牙齿方面均更具优势。
