Gupta Shweta, Ved Akash
Department of Pharmacy, Goel Institute of Pharmacy and Sciences, Lucknow, Uttar Pradesh, India.
Pharmacogn Rev. 2017 Jul-Dec;11(22):158-166. doi: 10.4103/phrev.phrev_6_17.
(Linn.) (OT) Silva Manso belongs to the family . This review incorporates literature for the phytochemical and pharmacological profile of OT herb. Exhaustive literature survey was done using all the details on phytochemistry and pharmacology of OT available. This herb was found to be a potent source of bioactive compounds such as α- and β-turpethein, turpethinic acids (A, B, C, D, and E), coumarins, cycloartenol, lanosta-5-ene, 24-methylene-δ-5-lanosterol, α- and β-rhamnose, β-sitosterol, lupeol, scopoletin, betulin, acrylamide, stigma-5,22dien-3-O-β-D-glucopyranoside, β-sitosterol-β-D-glucoside (H-1), 22,23-dihydro-α-spinosterol-β-D-glucoside (H-2), and salicylic acid (CH-2), which are useful in fevers, edema, ascites, anorexia, constipation, hepatosplenomegaly, hemorrhoids, cervical lymphadenitis, fistulas, constipation, chronic gout, fever, bronchitis, ulcers, hemorrhoids, tumors, obesity, jaundice, herpes, induce lacrimation, and other skin disorders. From the aerial parts of OT, four new dammarane-type saponins that are operculinosides A-D (1-4) were isolated that showed particular hepatoprotective activities. All the compounds are reported to possess pharmacological properties such as antibacterial, anti-inflammatory, analgesic, hepatoprotective, anti-arthritic, ulcer protective, antidiarrheal, antidiabetic, and cytotoxic properties.
（林奈）（OT）席尔瓦·曼索属于该科。本综述纳入了关于OT草药的植物化学和药理学特征的文献。利用所有可用的OT植物化学和药理学详细信息进行了详尽的文献调查。发现这种草药是生物活性化合物的重要来源，如α-和β-土荆芥素、土荆芥酸（A、B、C、D和E）、香豆素、环阿尔廷醇、羊毛甾-5-烯、24-亚甲基-δ-5-羊毛甾醇、α-和β-鼠李糖、β-谷甾醇、羽扇豆醇、东莨菪素、桦木醇、丙烯酰胺、柱头-5,22-二烯-3-O-β-D-葡萄糖苷、β-谷甾醇-β-D-葡萄糖苷（H-1）、22,23-二氢-α-菠菜甾醇-β-D-葡萄糖苷（H-2）和水杨酸（CH-2），这些化合物可用于治疗发热、水肿、腹水、厌食、便秘、肝脾肿大、痔疮、颈部淋巴结炎、瘘管、便秘、慢性痛风、发热、支气管炎、溃疡、痔疮、肿瘤、肥胖、黄疸、疱疹、催泪以及其他皮肤疾病。从OT的地上部分分离出了四种新的达玛烷型皂苷，即盖果皂苷A-D（1-4），它们具有特殊的保肝活性。据报道，所有这些化合物都具有抗菌、抗炎、镇痛、保肝、抗关节炎、溃疡保护、止泻、抗糖尿病和细胞毒性等药理特性。
