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无针接头:血管通路导管的微生物守护者。

Needleless connectors: the vascular access catheter's microbial gatekeeper.

作者信息

Curran Evonne

机构信息

Health Protection Scotland, UK.

出版信息

J Infect Prev. 2016 Sep;17(5):234-240. doi: 10.1177/1757177416657164. Epub 2016 Jul 25.

DOI:10.1177/1757177416657164
PMID:28989484
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5102078/
Abstract

Needleless connectors (NCs) are essential devices which connect to the end of vascular catheters and enable catheter access for infusion and aspiration. There are various different designs which make it difficult for purchasers to identify the features which present the least risk and greatest safety. The NC is the microbial gatekeeper for vascular catheters; how it is disinfected pre access determines if, and how many, organisms enter and how quickly biofilm will form. This paper will consider these design variations and how differences in antiseptic testing methods have made it difficult to determine the best antiseptic practice pre access. One specific design characteristic is considered: the fluid pathway. The NC's fluid pathway creates a flow which can be either direct to produce a laminar flow or indirect which creates a turbulent flow. At present, the evidence does not support there being an advantage for a specific fluid pathway design in reducing infection risks.

摘要

无针连接器(NCs)是连接到血管导管末端的重要装置,可实现通过导管进行输液和抽吸。有各种不同的设计,这使得购买者难以识别风险最小且安全性最高的特征。无针连接器是血管导管的微生物“守门人”;在使用前对其进行消毒的方式决定了是否有微生物进入以及进入多少微生物,以及生物膜形成的速度。本文将探讨这些设计差异,以及防腐测试方法的不同如何使得难以确定使用前的最佳防腐措施。本文考虑了一个特定的设计特征:流体通路。无针连接器的流体通路会产生一种流动,这种流动既可以是直接的以产生层流,也可以是间接的以产生湍流。目前,证据并不支持特定的流体通路设计在降低感染风险方面具有优势。

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本文引用的文献

1
Disinfection of Needleless Connector Hubs: Clinical Evidence Systematic Review.无针连接器接头的消毒:临床证据系统评价
Nurs Res Pract. 2015;2015:796762. doi: 10.1155/2015/796762. Epub 2015 May 14.
2
Meta-analysis on central line-associated bloodstream infections associated with a needleless intravenous connector with a new engineering design.关于一种采用新工程设计的无针静脉输液接头相关的中心静脉导管相关血流感染的荟萃分析。
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Impact of universal disinfectant cap implementation on central line-associated bloodstream infections.通用消毒帽的实施对中心静脉导管相关血流感染的影响。
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A successful approach to reducing bloodstream infections based on a disinfection device for intravenous needleless connector hubs.一种基于静脉无针连接器接头消毒装置的减少血流感染的成功方法。
J Infus Nurs. 2014 Nov-Dec;37(6):462-5. doi: 10.1097/NAN.0000000000000075.
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Blood stream infections due to OXA-48-like carbapenemase-producing Enterobacteriaceae: treatment and survival.产 OXA-48 类碳青霉烯酶肠杆菌科导致的血流感染:治疗与生存。
Int J Infect Dis. 2014 Sep;26:51-6. doi: 10.1016/j.ijid.2014.05.012. Epub 2014 Jul 3.
6
Use of bundled interventions, including a checklist to promote compliance with aseptic technique, to reduce catheter-related bloodstream infections in the intensive care unit.采用包括促进遵守无菌技术的检查表在内的综合干预措施,以减少重症监护病房中与导管相关的血流感染。
Paediatr Child Health. 2014 Apr;19(4):e20-3. doi: 10.1093/pch/19.4.e20.
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epic3: national evidence-based guidelines for preventing healthcare-associated infections in NHS hospitals in England.epic3:英格兰国民保健署医院内医源性感染预防的国家循证指南。
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8
Epidemiology and impact of a multifaceted approach in controlling central venous catheter associated blood stream infections outside the intensive care unit.重症监护病房外多方面措施控制中心静脉导管相关血流感染的流行病学及影响
BMC Infect Dis. 2013 Sep 24;13:445. doi: 10.1186/1471-2334-13-445.
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Adequate disinfection of a split-septum needleless intravascular connector with a 5-second alcohol scrub.用 5 秒酒精擦拭法对分体式无针血管内连接器进行充分消毒。
Infect Control Hosp Epidemiol. 2012 Jul;33(7):661-5. doi: 10.1086/666337. Epub 2012 May 8.
10
Impact of alcohol-impregnated port protectors and needleless neutral pressure connectors on central line-associated bloodstream infections and contamination of blood cultures in an inpatient oncology unit.酒精浸渍式端口保护器和无针中性压力连接器对住院肿瘤科中心静脉相关血流感染和血培养污染的影响。
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