Bikbov Mukharram, Fayzrakhmanov Rinat R, Kazakbaeva Gyulli, Jonas Jost B
a Ufa Eye Research Institute , Ufa , Bashkortostan , Russia.
b Department of Ophthalmology , Medical Faculty Mannheim of the Ruprecht-Karls-University of Heidelberg, Heidelberg , Germany.
Ophthalmic Epidemiol. 2018 Jun;25(3):187-198. doi: 10.1080/09286586.2017.1384504. Epub 2017 Oct 9.
Since there is a scarcity on population-based health information available for Russia, we conducted this project to assess the prevalence of major ocular and systemic disorders and their associated risk factors.
A population-based cross-sectional study (Ural Eye and Medical Study (UEMS)) was performed in Bashkortostan 1300 km east of Moscow. The sampling frame consisted of all inhabitants aged over 40 years and living in an urban study area in the capital city Ufa and a rural region at 65 km outside of Ufa. The target sample size was 2500 individuals for the urban region and 2500 persons for the rural region. The study participants underwent a detailed interview, a detailed ophthalmologic examination including biometry and optical coherence tomography, and clinical examination including assessment of electrocardiography, hearing test, blood sampling, spirometry, and hand grip dynamometry.
After a first study period, the study population included 4254 individuals with a mean age of 60.3 ± 11.1 years (range: 40-94 years), mean body weight of 74.8 ± 14.4 kg (range: 31-170 kg), body height of 163.6 ± 8.9 cm (range: 112-196), body mass index of 28.0 ± 5.1 kg/m (range: 13.96-60.96 kg/m), mean systolic blood pressure of 133.7 ± 21.0 mmHg (range: 84-232 mmHg), and mean diastolic blood pressure of 81.2 ± 10.6 mmHg (range: 40-134 mmHg). Mean refractive error was -0.21 ± 1.94 D and mean intraocular pressure was 13.6 ± 3.9 mmHg.
The UEMS provides population-based normative data for a Russian region on the quantitative traits such as axial length, quality of life and lifestyle including smoking and alcohol consumption, and prevalence and risk factors of ocular and systemic diseases such as diabetes mellitus, arterial hypertension, chronic obstructive pulmonary disease, and depression.
由于俄罗斯缺乏基于人群的健康信息，我们开展了本项目，以评估主要眼部和全身疾病的患病率及其相关危险因素。
在莫斯科以东1300公里的巴什基尔斯坦进行了一项基于人群的横断面研究（乌拉尔眼与医学研究（UEMS））。抽样框架包括所有年龄在40岁以上、居住在首都乌法的城市研究区域以及乌法以外65公里处农村地区的居民。城市地区的目标样本量为2500人，农村地区为2500人。研究参与者接受了详细访谈、包括生物测量和光学相干断层扫描的详细眼科检查，以及包括心电图评估、听力测试、血液采样、肺活量测定和握力测量在内的临床检查。
在第一个研究阶段后，研究人群包括4254人，平均年龄为60.3±11.1岁（范围：40 - 94岁），平均体重为74.8±14.4千克（范围：31 - 170千克），身高为163.6±8.9厘米（范围：112 - 196厘米），体重指数为28.0±5.1千克/米（范围：13.96 - 60.96千克/米），平均收缩压为133.7±21.0毫米汞柱（范围：84 - 232毫米汞柱），平均舒张压为81.2±10.6毫米汞柱（范围：40 - 134毫米汞柱）。平均屈光不正为-0.21±1.94屈光度，平均眼压为13.6±3.9毫米汞柱。
乌拉尔眼与医学研究（UEMS）为俄罗斯一个地区提供了基于人群的规范性数据，涉及诸如眼轴长度等定量特征、生活质量和包括吸烟及饮酒在内的生活方式，以及糖尿病、动脉高血压、慢性阻塞性肺疾病和抑郁症等眼部和全身疾病的患病率及危险因素。
