Lancet. 1988 Jul 16;2(8603):145-8.
The Egyptian National Control of Diarrheal Diseases Project (NCDDP) started in 1983. A field trial done in Dakahlia Governorate in 1980 to promote oral rehydration therapy showed that the mortality rate for the under-fives during the diarrhoea season was 18.1/1000 in control villages and 10.5/1000 in "outreach" villages (p less than 0.001). In 1986 mortality rates had become similar in the two areas and lower than in 1980 (6.5/1000 and 6.0/1000, respectively), even though there were no significant changes in diarrhoea incidence. Virtually all the reduction in mortality was due to a decline in diarrhoea-associated deaths. The principal differences between 1986 and 1980 were better case-management by mothers and doctors, in both outreach and control villages, and far greater television ownership. Village civil registers showed only slight changes in under-five mortality from all causes after 1980, but an accelerating decline from 1983. Governorate-wide civil registration data showed slowly falling infant death rates from 1970 onward, accelerating after 1982, with most of the decline corresponding to the seasonal pattern of diarrhoea-associated mortality throughout the year. Thus NCDDP promotion of better treatment seems to have been responsible for the decline in mortality.
埃及国家腹泻病控制项目(NCDDP)始于1983年。1980年在达卡利亚省进行的一项推广口服补液疗法的现场试验表明,腹泻季节5岁以下儿童的死亡率在对照村庄为18.1/1000,在“推广”村庄为10.5/1000(p<0.001)。1986年,这两个地区的死亡率变得相似且低于1980年(分别为6.5/1000和6.0/1000),尽管腹泻发病率没有显著变化。死亡率的几乎所有下降都归因于腹泻相关死亡人数的减少。1986年和1980年之间的主要差异在于,在推广村庄和对照村庄,母亲和医生的病例管理都有所改善,以及电视拥有量大幅增加。村庄民事登记显示,1980年后5岁以下儿童全因死亡率仅有轻微变化,但从1983年起下降加速。全省民事登记数据显示,自1970年起婴儿死亡率缓慢下降,1982年后加速下降,大部分下降与全年腹泻相关死亡率的季节性模式相对应。因此,NCDDP对更好治疗方法的推广似乎是死亡率下降的原因。