尼泊尔出现多种 NDM 型金属β-内酰胺酶产大肠埃希菌临床分离株。
Emergence of Various NDM-Type-Metallo-β-Lactamase-Producing Escherichia coli Clinical Isolates in Nepal.
机构信息
Department of Microbiology, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.
Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan
出版信息
Antimicrob Agents Chemother. 2017 Nov 22;61(12). doi: 10.1128/AAC.01425-17. Print 2017 Dec.
Abstract
Of 250 clinical isolates of obtained in Nepal, 38 were carbapenem resistant, with MICs of imipenem or meropenem of ≥4 μg/ml. All 38 isolates harbored the following s: , , , , , , and Most of these isolates also harbored the 16S rRNA methylase gene(s) , , and/or .
摘要
在尼泊尔获得的 250 株临床分离株中，有 38 株对碳青霉烯类药物耐药，亚胺培南或美罗培南的 MIC 值≥4μg/ml。所有 38 株分离株均携带以下基因：blaNDM-1、blaVIM-1、blaIMP-1、blaGES-5、blaSPM-1、blaVEB-1 和 blaCTX-M-15。这些分离株大多数还携带 16S rRNA 甲基化酶基因（s）armA、catB8 和/或 mphA。
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