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脂肪性头皮水肿:与腮腺脂肪浸润有关联吗?

Lipoedematous scalp: is there an association with fatty infiltration of the parotid?

作者信息

Law Sarah, Jayarajan Rajshree

机构信息

Department of Plastic Surgery, Leicester Royal Infirmary, Leicester, UK.

出版信息

BMJ Case Rep. 2017 Oct 9;2017:bcr-2017-220808. doi: 10.1136/bcr-2017-220808.

DOI:10.1136/bcr-2017-220808
PMID:28993353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5652518/
Abstract

Lipoedematous scalp (LS) is an extremely rare condition characterised by a soft and boggy consistency in the scalp due to an increased layer of subcutaneous tissue.In this report, we present a case of LS in a 64-year-old Indian woman. Clinical examination revealed only vague boggy lumpiness involving the whole of occipital scalp extending to parietal scalp. MRI scalp showed diffuse fatty infiltration of the scalp, particularly at the posterior parietal and occipital convexity extending to both lateral aspects of the cranium, with homogeneous signal in keeping with fat. Incidentally MRI also found diffuse fatty infiltration of the parotids.The aethiopathogenesis of LS is still unknown, however it is believed that the hormone leptin could be the key hormone in the dysregulation of fat deposition and distribution. This case report highlights the subtle features with which these cases can present and explores the literature on reported cases of LS.

摘要

脂肪性头皮水肿(LS)是一种极为罕见的病症,其特征是由于皮下组织层增厚,头皮质地柔软且呈肿胀状。在本报告中,我们呈现了一名64岁印度女性患脂肪性头皮水肿的病例。临床检查仅发现枕部头皮弥漫性肿胀,延伸至顶叶头皮,质地模糊。头皮磁共振成像(MRI)显示头皮弥漫性脂肪浸润,尤其是顶叶后部和枕叶凸面,延伸至颅骨两侧,信号均匀,符合脂肪特征。偶然间,MRI还发现腮腺弥漫性脂肪浸润。脂肪性头皮水肿的发病机制尚不清楚,但人们认为激素瘦素可能是脂肪沉积和分布失调的关键激素。本病例报告强调了这些病例可能呈现的细微特征,并探讨了有关脂肪性头皮水肿报告病例的文献。

相似文献

1
Lipoedematous scalp: is there an association with fatty infiltration of the parotid?脂肪性头皮水肿:与腮腺脂肪浸润有关联吗?
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本文引用的文献

1
Lipedematous alopecia: clinical and histological analysis of the first male Chinese.脂肿性秃发:首例中国男性患者的临床及组织学分析
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Self-Care for Management of Secondary Lymphedema: A Systematic Review.继发性淋巴水肿管理的自我护理:一项系统综述
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[Adipocytic tumors of the salivary glands: A retrospective study].[唾液腺脂肪细胞性肿瘤:一项回顾性研究]
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Successful treatment of lipedematous alopecia using mycophenolate mofetil.霉酚酸酯成功治疗脂肪性脱发
Acta Derm Venereol. 2015 Nov;95(8):1011-2. doi: 10.2340/00015555-2114.
5
Congenital lipedematous alopecia: adding to the differential diagnosis of congenital alopecia.先天性脂肪性脱发:补充先天性脱发的鉴别诊断。
Ann Dermatol. 2015 Feb;27(1):87-9. doi: 10.5021/ad.2015.27.1.87. Epub 2015 Feb 3.
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Lipedematous scalp.
Indian J Dermatol Venereol Leprol. 2014 May-Jun;80(3):270-2. doi: 10.4103/0378-6323.132266.
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Lipid infiltration in the parotid glands: a clinical manifestation of metabolic syndrome.
Exp Clin Endocrinol Diabetes. 2012 Feb;120(2):110-5. doi: 10.1055/s-0031-1291315. Epub 2011 Nov 8.
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Clinical and pathological features of 31 cases of lipedematous scalp and lipedematous alopecia.31 例脂肪性头皮和脂肪性脱发的临床和病理特征。
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[Lipedematous scalp with early onset].[早期发病的脂性头皮]
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Successful surgical management of lipoedematous alopecia.脂肪性水肿性脱发的成功手术治疗
Australas J Dermatol. 2008 Feb;49(1):52-4. doi: 10.1111/j.1440-0960.2007.00427.x.