From Division of Cardiology, Queen's University, Kingston, Ontario, Canada.
Circulation. 2017 Oct 10;136(15):1434-1448. doi: 10.1161/CIRCULATIONAHA.117.030387.
Alcoholic beverages have been consumed for thousands of years, attracting great human interest for social, personal, and religious occasions. In addition, they have long been debated to confer cardioprotective benefits. The French Paradox is an observation of a low prevalence of ischemic heart disease, with high intakes of saturated fat, a phenomenon accredited to the consumption of red wine. Although many epidemiological investigations have supported this view, others have attributed it to beer or spirits, with many suggesting that the drink type is not important. Although excessive consumption of alcoholic beverages is commonly regarded to be detrimental to cardiovascular health, there is a debate as to whether light-to-moderate intake is cardioprotective. Although there is extensive epidemiological support for this drinking pattern, a consensus has not been reached. On the basis of published work, we describe the composition of wine and the effects of constituent polyphenols on chronic cardiovascular diseases.
酒精饮料已经被人类饮用了数千年，无论是社交、个人还是宗教场合，它们都吸引着人们的极大兴趣。此外，它们长期以来一直被认为具有心脏保护作用。法国悖论是指在摄入大量饱和脂肪的情况下，缺血性心脏病的发病率较低，这一现象归因于饮用红酒。尽管许多流行病学调查支持这一观点，但也有人认为这与啤酒或烈酒有关，许多人认为饮酒类型并不重要。尽管过量饮酒通常被认为对心血管健康有害，但对于轻至中度饮酒是否具有心脏保护作用仍存在争议。尽管这种饮酒模式有广泛的流行病学支持，但尚未达成共识。根据已发表的研究，我们描述了葡萄酒的成分以及其组成多酚对慢性心血管疾病的影响。
