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[心血管疾病的预防与发酵酒精饮料。现实还是虚构?]

[Prevention of cardiovascular disease and fermented alcoholic beverages. Reality or fiction?].

作者信息

Sacanella Anglés Ignasi, Casas Rodríguez Rosa, Viñas Esmel Esther, Castro Barquero Sara, Sacanella Meseguer Emilio

机构信息

Hospital Clínic.

出版信息

Nutr Hosp. 2019 Aug 27;36(Spec No3):58-62. doi: 10.20960/nh.02811.

DOI:10.20960/nh.02811
PMID:31368340
Abstract

A large evidence-based reports a J-shaped association among moderate alcohol consumption and cardiovascular health. Low-moderate alcohol intake has been related to lower all-cause mortality (20%) and ischemic heart events (40%) compared to abstainers. The dose that is allegedly beneficial varies between 10-20 gr/day for women and men respectively. Moreover, the drinking pattern seems to be significant in order to get healthy effects. Moderate alcohol consumption hinders atherogenesis by several mechanisms mainly improving lipid profile and reducing thrombogenesis. Nevertheless, it is still unclear whether high-polyphenol alcoholic beverages, such as wine and beer, confer a greater cardiovascular protection than spirits, which have much less polyphenol content.

摘要

一项基于大量证据的报告显示,适度饮酒与心血管健康之间呈J形关联。与戒酒者相比,低至适度饮酒与全因死亡率降低(20%)和缺血性心脏事件降低(40%)有关。据称,对女性和男性有益的饮酒量分别为每天10 - 20克。此外,为了获得健康益处,饮酒模式似乎也很重要。适度饮酒通过多种机制阻碍动脉粥样硬化的发生,主要是改善血脂状况和减少血栓形成。然而,高多酚酒精饮料,如葡萄酒和啤酒,是否比多酚含量低得多的烈酒具有更大的心血管保护作用仍不清楚。

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1
[Prevention of cardiovascular disease and fermented alcoholic beverages. Reality or fiction?].[心血管疾病的预防与发酵酒精饮料。现实还是虚构?]
Nutr Hosp. 2019 Aug 27;36(Spec No3):58-62. doi: 10.20960/nh.02811.
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Effects of wine, alcohol and polyphenols on cardiovascular disease risk factors: evidences from human studies.葡萄酒、酒精和多酚对心血管疾病危险因素的影响:来自人体研究的证据。
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Mortality associated with moderate intakes of wine, beer, or spirits.与适度饮用葡萄酒、啤酒或烈酒相关的死亡率。
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Wine, beer or spirit drinking in relation to fatal and non-fatal cardiovascular events: a meta-analysis.饮酒与致命和非致命心血管事件的关系:荟萃分析。
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Association between alcohol consumption and all-cause mortality, cardiovascular disease, and chronic kidney disease: A prospective cohort study.饮酒与全因死亡率、心血管疾病和慢性肾脏病的关系:一项前瞻性队列研究。
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Effects of alcohol and polyphenols from beer on atherosclerotic biomarkers in high cardiovascular risk men: a randomized feeding trial.啤酒中的酒精和多酚对心血管高危男性动脉粥样硬化生物标志物的影响:一项随机喂养试验。
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