Ketterer R, Frenk E
Service de dermatologie, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne.
Ther Umsch. 1995 Apr;52(4):269-74.
Endocrinologic disorders occasionally manifest themselves by cutaneous abnormalities. In some instances, these alterations are the most prominent complaints of the patient. It is then important that the physician is able to recognize them as the manifestation of the endocrinologic disease. In this review, we describe the main cutaneous lesions occurring in endocrinopathy, like troubles of the skin pigmentation [melasma, acanthosis nigricans, Addison's disease, Cushing's syndrome, vitiligo], generalized or pretibial myxedema, acne and androgen excess, hirsutism. Where known, we try to approach the physiopathologic mechanisms that account for cutaneous changes. Additionally, some treatments are discussed.
内分泌紊乱偶尔会通过皮肤异常表现出来。在某些情况下，这些改变是患者最突出的症状。因此，医生能够将其识别为内分泌疾病的表现很重要。在本综述中，我们描述了内分泌病中出现的主要皮肤病变，如皮肤色素沉着问题（黄褐斑、黑棘皮病、艾迪生病、库欣综合征、白癜风）、全身性或胫前黏液性水肿、痤疮和雄激素过多、多毛症。在已知的情况下，我们试图探讨导致皮肤变化的生理病理机制。此外，还讨论了一些治疗方法。
